US4248704A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Phenylalanine ammonia lyase occluded fibers for reducing phenylalanine blood-level
Assignee: Anic SpA
•
Filing: 1979-05-03
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Granted: 1981-02-03
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Expires: 1999-05-03
Abstract
Abstract Phenylalanine level in blood or another medium is considerably reduced and can even be annulled by causing blood or the other medium to flow through a mass of porous fibers in which the enzyme phenylalanine ammonia lyase has been occluded: the fibers have been previously made biocompatible, if necessary.
Inventors
- 👤 Walter Marconi
- 👤 Francesco Bartoli
- 👤 Roberto Gianna
- 👤 Franco Morisi
- 👤 Giuseppina Spotorno
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 21:10
CPC Classifications
C; C12; C12N; C12N11/00; C12N11/02; C12N11/04; A; A23; A23J; A23J3/00; A23J3/30; A61; A61M; A61M1/00; A61M1/36; A61M1/3687; A61P; A61P3/00
Claims Analysis
Total Claims: 2
Claim 1
Independent Claim
51 words
Method for the reduction of the phenylalanine level in blood or another medium containing phenylalanine, consisting in contacting said blood or said media with a composition which comprises the enzyme phenylalanine ammonia lyase occluded in porous fibers of cellulose triacetate which have been made biocompatible by dispersing therein 4,5-diphenyl-2-bis(2-hydroxyethyl) amino oxazole.
Claim 2
Dependent Claim
51 words
Method for the reduction of the phenylalanine level in blood or another medium containing phenylalanine, consisting in contacting said blood or said media with a composition which comprises the enzyme phenylalanine ammonia lyase occluded in porous fibers of cellulose triacetate which have been made biocompatible by dispersing therein 4,5-diphenyl-2-bis(2-hydroxyethyl) amino oxazole.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1984-02-03 | 1984-08-04 | 1985-02-03 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1988-02-03 | 1988-08-04 | 1989-02-03 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1992-02-03 | 1992-08-04 | 1993-02-03 | $7700.00 | Window Closed / Lapsed |