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Folic acid derivatives for use in radioimmunoassay

Assignee: Abbott Laboratories
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Filing: 1978-09-13
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Granted: 1981-01-27
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Expires: 1998-09-13
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Abstract

Abstract The present invention encompasses compounds I and II, mixtures of I and II and acid addition salts thereof wherein R is hydrogen or loweralkyl having 1-3 carbon atoms, as well as compounds wherein the phenol moiety is labeled with 125 I or 131 I. The radiolabeled compounds are useful in radiochemical assaying for folic acid. ##STR1##

Inventors

  • 👤 Akhtar Ali

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-11-04 16:43
CPC Classifications
G; G01; G01N; G01N33/00; G01N33/48; G01N33/50; G01N33/82; C; C07; C07K; C07K5/00; C07K5/02; C07K5/0215; C07K5/04; C07K5/06; C07K5/06008; C07K5/06078; C07K5/08; C07K5/0819; Y; Y10; Y10S; Y10S436/00; Y10S436/804; Y10S436/815

Claims Analysis

Total Claims: 4
Claim 1
Independent Claim 31 words
A compound of the formula I or II, ##STR5## and acid addition salts thereof wherein R is hydrogen and wherein the phenol ring is labeled with 125 I or 131 I.
Claim 2
Dependent Claim 31 words
A compound of the formula I or II, ##STR5## and acid addition salts thereof wherein R is hydrogen and wherein the phenol ring is labeled with 125 I or 131 I.
Claim 3
Dependent Claim 30 words
A mixture of compounds I and II ##STR6## and acid addition salts thereof wherein R is hydrogen and wherein the phenol ring is labeled with 125 I or 131 I.
Claim 4
Dependent Claim 30 words
A mixture of compounds I and II ##STR6## and acid addition salts thereof wherein R is hydrogen and wherein the phenol ring is labeled with 125 I or 131 I.

References Cited (Backward Citations)

US3989812A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1984-01-27 1984-07-28 1985-01-27 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1988-01-27 1988-07-28 1989-01-27 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1992-01-27 1992-07-28 1993-01-27 $7700.00 Window Closed / Lapsed

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