Patent US4241044A successfully refreshed from Google Patents.
US4241044A
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Method of diagnosing cancer by detecting elevated anti-T antibody activity
Assignee: Abbott Laboratories
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Filing: 1978-12-28
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Granted: 1980-12-23
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Expires: 1998-12-28
Abstract
Abstract This application discloses a method for diagnosing cancer by employing any of various immunochemical procedures to detect elevated levels of anti-(blood group T antigen) antibodies in a biological sample.
Inventors
- 👤 Yung D. Kim
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-01 06:45
CPC Classifications
G; G01; G01N; G01N33/00; G01N33/48; G01N33/50; G01N33/53; G01N33/575; G01N33/5758; G01N33/57585; Y; Y10; Y10S; Y10S436/00; Y10S436/804; Y10S436/811; Y10S436/813; Y10S530/00; Y10S530/806; Y10S530/827; Y10S530/828
Claims Analysis
Total Claims: 10
Claim 1
Independent Claim
21 words
A method of diagnosing cancer which comprises immunochemically detecting elevated anti-T antibody activity in a biological sample from an untreated individual.
Claim 2
Independent Claim
21 words
A method of diagnosing cancer which comprises immunochemically detecting elevated anti-T antibody activity in a biological sample from an untreated individual.
Claim 3
Dependent Claim
14 words
A method according to claim 1 in which the biological sample is human serum.
Claim 4
Dependent Claim
14 words
A method according to claim 1 in which the biological sample is pleural fluid.
Claim 5
Dependent Claim
10 words
A method according to claim 1 which employs a radioimmunoassay.
Claim 6
Dependent Claim
10 words
A method according to claim 1 which employs radiolabled T-antigen.
Claim 7
Dependent Claim
13 words
A method according to claim 1 which employs a solid phase immunoassay system.
Claim 8
Dependent Claim
12 words
A method according to claim 1 which employs an immune-complex precipitation system.
Claim 9
Independent Claim
101 words
A method of diagnosing cancer by detecting elevated levels of anti-T antibody which comprises: mixing a biological sample from a therapeutically untreated individual with a known amount of labeled T-antigen and anti-T antibody affixed to a solid support; allowing the affixed antibody to compete with any anti-T antibody in said sample and selectively complex with the labeled T-antigen; separating the solid support from the reaction medium; measuring the degree of binding of the labeled T-antigen with the affixed anti-T antibody; and determining the amount of anti-T antibody present in said sample by comparing the degree of binding to a standard curve.
Claim 10
Independent Claim
101 words
A method of diagnosing cancer by detecting elevated levels of anti-T antibody which comprises: mixing a biological sample from a therapeutically untreated individual with a known amount of labeled T-antigen and anti-T antibody affixed to a solid support; allowing the affixed antibody to compete with any anti-T antibody in said sample and selectively complex with the labeled T-antigen; separating the solid support from the reaction medium; measuring the degree of binding of the labeled T-antigen with the affixed anti-T antibody; and determining the amount of anti-T antibody present in said sample by comparing the degree of binding to a standard curve.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1983-12-23 | 1984-06-23 | 1984-12-23 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1987-12-23 | 1988-06-23 | 1988-12-23 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1991-12-23 | 1992-06-23 | 1992-12-23 | $7700.00 | Window Closed / Lapsed |