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US4235914A Expired / Lapsed US ⏱️ 0.0 years remaining

Psychotropic γ-(heterocyclic substituted) butyrophenones

Assignee: Sumitomo Chemical Co Ltd
•
Filing: 1978-10-17
•
Granted: 1980-11-25
•
Expires: 1998-10-17
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Abstract

Abstract Butyrophenone compounds having excellent psychotropic activity and represented by the formula: ##STR1## wherein Z is defined hereinbelow.

Inventors

  • 👤 Kikuo Sasajima
  • 👤 Keiichi Ono
  • 👤 Hisao Yamamoto

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-11-08 04:53
CPC Classifications
C; C07; C07D; C07D295/00; C07D295/04; C07D295/10; C07D295/104; C07D295/108; C07D211/00; C07D211/04; C07D211/06; C07D211/08; C07D211/18; C07D211/30; C07D211/32; C07D211/36; C07D211/40; C07D211/44; C07D211/52

Claims Analysis

Total Claims: 9
Claim 1
Independent Claim 9 words
γ-[4-(3-Trifluoromethylphenyl)-4-hydroxypiperidino]-2-hydroxy-4-fluorobutyrophenone, or a pharmaceutically acceptable acid addition salt thereof.
Claim 2
Dependent Claim 9 words
γ-[4-(3-Trifluoromethylphenyl)-4-hydroxypiperidino]-2-hydroxy-4-fluorobutyrophenone, or a pharmaceutically acceptable acid addition salt thereof.
Claim 3
Dependent Claim 9 words
γ-[4-(2-Keto-1-benzimidazolinyl)piperidin-1-yl]-2-hydroxy-4-fluorobutyrophenone, or a pharmaceutically acceptable acid addition salt thereof.
Claim 4
Dependent Claim 9 words
γ-[4-(2-Keto-1-benzimidazolinyl)piperidin-1-yl]-2-hydroxy-4-fluorobutyrophenone, or a pharmaceutically acceptable acid addition salt thereof.
Claim 5
Dependent Claim 9 words
γ-[4-Oxo-1-phenyl-1,3,8-triazaspiro[4,5]-decan-8-yl]-2-hydroxy-4-fluorobutyrophenone, or a pharmaceutically acceptable acid addition salt thereof.
Claim 6
Dependent Claim 9 words
γ-[4-Oxo-1-phenyl-1,3,8-triazaspiro[4,5]-decan-8-yl]-2-hydroxy-4-fluorobutyrophenone, or a pharmaceutically acceptable acid addition salt thereof.
Claim 7
Dependent Claim 41 words
An antipsychotic composition comprising an effective antipsychotic amount of at least one of the compounds as claimed in any one of claims 1, 2 or 3 or a pharmaceutically acceptable salt thereof, and at least one pharmaceutically acceptable diluent or carrier.
Claim 8
Independent Claim 33 words
A method of treating a patient suffering from mental disease which comprises administering to said patient an effective psychotropic amount of a compound according to any one of claims 1, 2 or 3.
Claim 9
Dependent Claim 22 words
The method according to claim 5, wherein from 1 to 200 mg. of said compound is administered orally to the patient daily.

References Cited (Backward Citations)

US3799932A Cited
JPS4718878U Cited
US3979390A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1983-11-25 1984-05-26 1984-11-25 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1987-11-25 1988-05-26 1988-11-25 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1991-11-25 1992-05-26 1992-11-25 $7700.00 Window Closed / Lapsed

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