Patent US4234584A successfully refreshed from Google Patents.
US4234584A
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Substituted phenylpiperazine derivatives
Assignee: Hoechst AG
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Filing: 1979-06-04
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Granted: 1980-11-18
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Expires: 1999-06-04
Abstract
Abstract Phenylpiperazine derivatives of the formula I ##STR1## in which R 1 denotes hydrogen or C 1 -C 6 alkyl, R 2 denotes hydrogen or one or several, identical or different substituents selected from the group of C 1 -C 6 -alkyl, C 1 -C 6 alkoxy, halogen, trifluoromethyl, hydroxy, nitro, amino and methylene-dioxy, R 3 denotes hydrogen, hydroxy, C 1 -C 6 alkanoyloxy, and n is 1 or 2, and the physiologically acceptable salts thereof, processes for their manufacture and medicaments containing or consisting of said compounds.
Inventors
- 👤 Rudolf Lattrell
- 👤 Wilhelm Bartmann
- 👤 Hermann Gerhards
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-28 13:46
CPC Classifications
C; C07; C07D; C07D209/00; C07D209/02; C07D209/04; C07D209/08; C07D209/30; C07D209/32; C07D209/34; C07D215/00; C07D215/02; C07D215/16; C07D215/38
Claims Analysis
Total Claims: 5
Claim 1
Independent Claim
73 words
A phenylpiperazine compound of the formula ##STR25## or a physiologically acceptable salt thereof, wherein R 1 denotes hydrogen or C 1 -C 6 alkyl, R 2 denotes one or several, identical or different, members selected from the group consisting of C 1 -C 6 -alkyl, C 1 -C 6 alkoxy, halogen, trifluoromethyl, hydroxy, nitro, amino, and methylene-dioxy, R 3 denotes hydrogen, hydroxy, C 1 -C 6 alkanoyloxy, and n is 1 or 2.
Claim 2
Dependent Claim
73 words
A phenylpiperazine compound of the formula ##STR25## or a physiologically acceptable salt thereof, wherein R 1 denotes hydrogen or C 1 -C 6 alkyl, R 2 denotes one or several, identical or different, members selected from the group consisting of C 1 -C 6 -alkyl, C 1 -C 6 alkoxy, halogen, trifluoromethyl, hydroxy, nitro, amino, and methylene-dioxy, R 3 denotes hydrogen, hydroxy, C 1 -C 6 alkanoyloxy, and n is 1 or 2.
Claim 3
Dependent Claim
20 words
A neuroleptic composition comprising a compound as defined in claim 1 and a physiologically acceptable auxiliary agent or carrier therefor.
Claim 4
Dependent Claim
36 words
The method of treating a human patient to produce a neuroleptic effect which comprises orally administering to said patient of a dose of about 20 to 800 mg/day of a compound as defined in claim 1.
Claim 5
Dependent Claim
35 words
The method of treating a human patient to produce a neuroleptic effect which comprises intravenously administering to said patient a dose of about 5 to 300 mg/day of a compound as defined in claim 1.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1983-11-18 | 1984-05-19 | 1984-11-18 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1987-11-18 | 1988-05-19 | 1988-11-18 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1991-11-18 | 1992-05-19 | 1992-11-18 | $7700.00 | Window Closed / Lapsed |