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US4232121A Expired / Lapsed US ⏱️ 0.0 years remaining

Process for selecting methine dyes which inhibit cell growth

Assignee: Eastman Kodak Co
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Filing: 1978-09-25
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Granted: 1980-11-04
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Expires: 1998-09-25
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Abstract

Abstract Methine dyes which inhibit cell growth are identified by (1) determining the reduction potential of the dye, (2) determining the ability of the dye to sorb to the cells and (3) selecting those dyes which have a reduction potential more negative than about -0.8 volt and which are sorbed to the cells.

Inventors

  • 👤 Paul B. Gilman, Jr.
  • 👤 Robert T. Belly
  • 👤 Thaddeus D. Koszelak
  • 👤 Seymour Zigman

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-30 23:55
CPC Classifications
C; C09; C09B; C09B23/00; C09B23/02; C09B23/04; A; A01; A01N; A01N43/00; A01N43/34; A01N43/36; A01N43/38; A01N43/40; A01N43/42; A01N43/72; A01N43/74; A01N43/90; A01N61/00; A61; A61L; A61L2/00; A61L2/16; A61L2/18; C09B23/06; C09B23/08; C09B23/083; C09B23/16; C09B23/162; C09B23/166; C12; C12Q; C12Q1/00; C12Q1/02; C12Q1/18

Claims Analysis

Total Claims: 13
Claim 1
Independent Claim 66 words
A process for selecting methine dyes which inhibit cell growth, the process comprising (1) determining the reduction potential (E R ) of the dyes, (2) determining the ability of the dyes to bind to the cells and (3) selecting those dyes which have a reduction potential more negative than about 31 0.8 volt and which bind to the cells to the extent of 10% or greater.
Claim 2
Dependent Claim 66 words
A process for selecting methine dyes which inhibit cell growth, the process comprising (1) determining the reduction potential (E R ) of the dyes, (2) determining the ability of the dyes to bind to the cells and (3) selecting those dyes which have a reduction potential more negative than about 31 0.8 volt and which bind to the cells to the extent of 10% or greater.
Claim 3
Dependent Claim 19 words
A process of claim 1 wherein the dyes selected have a reduction potential more negative than about -1.0 volt.
Claim 4
Dependent Claim 12 words
A process of claim 1 wherein the dyes selected are cyanine dyes.
Claim 5
Dependent Claim 17 words
A process of claim 1 wherein the dyes are selected to inhibit the growth of procaryotic cells.
Claim 6
Dependent Claim 17 words
A process of claim 1 wherein the dyes are selected to inhibit the growth of eucaryotic cells.
Claim 7
Dependent Claim 32 words
A process for inhibiting cell growth comprising the steps of: (1) selecting a dye by the process of claim 1, and (2) contacting the cells to be inhibited with the selected type.
Claim 8
Dependent Claim 33 words
A process for manufacturing a cell growth inhibitory composition comprising the steps of: (1) selecting a dye by the process of claim 1, and (2) combining the selected dye with a non-interferring carrier.
Claim 9
Dependent Claim 69 words
A process for selecting antimicrobial methine dyes, the process comprising (1) determining the reduction potential (E R ) of the dyes, (2) determining the ability of the dyes to bind to the cells of the microbes and (3) selecting an antimicrobial agents those dyes which have a reduction potential more negative than about -0.8 volt and which bind to the microbial cells to the extent of 10% or greater.
Claim 10
Dependent Claim 69 words
A process for selecting antimicrobial methine dyes, the process comprising (1) determining the reduction potential (E R ) of the dyes, (2) determining the ability of the dyes to bind to the cells of the microbes and (3) selecting an antimicrobial agents those dyes which have a reduction potential more negative than about -0.8 volt and which bind to the microbial cells to the extent of 10% or greater.
Claim 11
Dependent Claim 19 words
A process of claim 8 wherein the dyes selected have a reduction potential more negative than about -1.0 volt.
Claim 12
Dependent Claim 12 words
A process of claim 8 wherein the dyes selected are cyanine dyes.
Claim 13
Dependent Claim 16 words
A process of claim 8 wherein the dyes are selected to inhibit the growth of bacteria.

References Cited (Backward Citations)

No citation records indexed.

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1983-11-04 1984-05-05 1984-11-04 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1987-11-04 1988-05-05 1988-11-04 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1991-11-04 1992-05-05 1992-11-04 $7700.00 Window Closed / Lapsed

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