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US4232028A
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US
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17-Cyclobutylmethyl-4,5α-epoxy-3-hydroxy-14-methoxy-8α-methylmorphinan-6-one, and method of treating pain with it
Assignee: Sisa Inc
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Filing: 1979-06-18
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Granted: 1980-11-04
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Expires: 1999-06-18
Abstract
Abstract Disclosed is 17-cyclobutylmethyl-4,5α-epoxy-3-hydroxy-14-methoxy-8α-methylmorphinan-6-one characterized by the formula: ##STR1## This compound is useful as a mixed analgesic/narcotic antagonist.
Inventors
- 👤 Raj K. Razdan
- 👤 Anil C. Ghosh
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-06 08:35
CPC Classifications
C; C07; C07D; C07D489/00; C07D489/06; C07D489/08
Claims Analysis
Total Claims: 8
Claim 1
Independent Claim
6 words
17-cyclbutylmethyl-4,5α-epoxy-3-hydroxy-14-methoxy-8α:methylmorphinan-6-one characterized by the formula: ##STR8##
Claim 2
Dependent Claim
6 words
17-cyclbutylmethyl-4,5α-epoxy-3-hydroxy-14-methoxy-8α:methylmorphinan-6-one characterized by the formula: ##STR8##
Claim 3
Dependent Claim
16 words
The compound defined by claim 1 in the form of its pharmacologically acceptable acid addition salt.
Claim 4
Dependent Claim
12 words
The hydrochloric acid addition salt of the compound defined by claim 1.
Claim 5
Dependent Claim
37 words
A therapeutic method for treating pain without liability of drug dependence in an individual for whom such therapy is indicated which method comprises administering an effective analgesic amount of a compound corresponding to the structural formula: ##STR9##
Claim 6
Dependent Claim
37 words
A therapeutic method for treating pain without liability of drug dependence in an individual for whom such therapy is indicated which method comprises administering an effective analgesic amount of a compound corresponding to the structural formula: ##STR9##
Claim 7
Dependent Claim
20 words
The method of claim 4 wherein the compound is administered in the form of its pharmacologically acceptable acid addition salt.
Claim 8
Dependent Claim
19 words
The method of claim 4 wherein the compound is administered in the form of its hydrochloric acid addition salt.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1983-11-04 | 1984-05-05 | 1984-11-04 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1987-11-04 | 1988-05-05 | 1988-11-04 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1991-11-04 | 1992-05-05 | 1992-11-04 | $7700.00 | Window Closed / Lapsed |