Patent US4229534A successfully refreshed from Google Patents.
US4229534A
Expired / Lapsed
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Acetylthienamycin production
Assignee: Merck and Co Inc
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Filing: 1979-04-05
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Granted: 1980-10-21
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Expires: 1999-04-05
Abstract
Abstract The antibiotic N-acetyl thienamycin and its non-toxic pharmaceutically acceptable salts are active against both gram-positive and gram-negative bacteria. The antiobiotic is produced by growing a species of Streptomyces on suitable fermentation media or alternatively by acetylation of thienamycin.
Inventors
- 👤 Jean S. Kahan
- 👤 Frederick M. Kahan
- 👤 Robert T. Goegelman
- 👤 Edward O. Stapley
- 👤 Sebastian Hernandez
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-27 07:07
CPC Classifications
C; C07; C07D; C07D477/00; C07D477/10; C07D477/12; C07D477/16; C07D477/20; C12; C12N; C12N1/00; C12N1/20; C12N1/205; C12P; C12P17/00; C12P17/18; C12P17/182; C12P17/184; C12R; C12R2001/00; C12R2001/01; C12R2001/465; Y; Y10; Y10S; Y10S435/00; Y10S435/8215; Y10S435/822; Y10S435/886
Claims Analysis
Total Claims: 3
Claim 1
Independent Claim
38 words
A process for the production of N-acetyl thienamycin which comprises cultivating Streptomyces cattleya in an aqueous nutrient medium containing assimilable sources of carbon, nitrogen and inorganic salts under submerged aerobic conditions and recovering the N-acetyl thienamycin so produced.
Claim 2
Dependent Claim
38 words
A process for the production of N-acetyl thienamycin which comprises cultivating Streptomyces cattleya in an aqueous nutrient medium containing assimilable sources of carbon, nitrogen and inorganic salts under submerged aerobic conditions and recovering the N-acetyl thienamycin so produced.
Claim 3
Dependent Claim
14 words
The process of claim 1 wherein the microorganism cultivated is Streptomyces cattleya NRRL 8057.
References Cited (Backward Citations)
US4006060A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1983-10-21 | 1984-04-21 | 1984-10-21 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1987-10-21 | 1988-04-21 | 1988-10-21 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1991-10-21 | 1992-04-21 | 1992-10-21 | $7700.00 | Window Closed / Lapsed |