US4229430A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Oral composition for improving oral health
Assignee: Individual
•
Filing: 1978-08-21
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Granted: 1980-10-21
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Expires: 1998-08-21
Abstract
Abstract A therapeutic composition is disclosed for use in improving the physiological tone of the oral tissues, which among other beneficial effects nourishes said tissues and causes them to approach normal condition. The therapeutic composition also has an antimicrobial effect on the oral microflora including those difficult to eliminate pathogenic genera known to be implicated in dental caries and periodontal disease. The therapeutic composition comprises a pharmaceutically acceptable, water soluble zinc salt and ascorbic acid or an active analog thereof. The zinc salt and the ascorbic acid are present in an amount sufficient to provide a synergistic combination which has a greater than additive antimicrobial effect on such oral genera as Actinomyces, Streptococcus, Staphylococcus, Candida, Pseudomonas and Escherichia.
Inventors
- 👤 Mostafa S. Fahim
- 👤 Ercell L. Miller
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-01 09:23
CPC Classifications
A; A61; A61K; A61K8/00; A61K8/18; A61K8/30; A61K8/67; A61K8/676; A61K8/19; A61K8/27; A61Q; A61Q11/00
Claims Analysis
Total Claims: 15
Claim 1
Independent Claim
46 words
A therapeutic composition for topical oral administration for stimulating production of collagen consisting essentially of about 0.5 to about 2.0 percent by weight/volume of a pharmaceutically acceptable, water soluble zinc salt and about 0.5 to about 2.0 percent by weight/volume of ascorbic acid or sodium ascorbate.
Claim 2
Dependent Claim
46 words
A therapeutic composition for topical oral administration for stimulating production of collagen consisting essentially of about 0.5 to about 2.0 percent by weight/volume of a pharmaceutically acceptable, water soluble zinc salt and about 0.5 to about 2.0 percent by weight/volume of ascorbic acid or sodium ascorbate.
Claim 3
Dependent Claim
27 words
The composition according to claim 1 wherein the ratio of the zinc salt to the ascorbic acid or sodium ascorbate is substantially 1 to 1 by weight.
Claim 4
Dependent Claim
17 words
The composition according ing to claim 2 wherein the zinc salt is ZnSO 4 .7H 2 O.
Claim 5
Dependent Claim
16 words
The composition according to claim 3 wherein the pH is from about 4 to about 5.
Claim 6
Independent Claim
57 words
A method for treating oral tissues by stimulating the production of collagen comprising topically administering thereto a therapeutically effective amount of a composition consisting essentially of about 0.5 to about 2.0 percent by weight/volume of a pharmaceutically acceptable, water soluble zinc salt and about 0.5 to about 2.0 percent by weight/volume of ascorbic acid or sodium ascorbate.
Claim 7
Independent Claim
57 words
A method for treating oral tissues by stimulating the production of collagen comprising topically administering thereto a therapeutically effective amount of a composition consisting essentially of about 0.5 to about 2.0 percent by weight/volume of a pharmaceutically acceptable, water soluble zinc salt and about 0.5 to about 2.0 percent by weight/volume of ascorbic acid or sodium ascorbate.
Claim 8
Dependent Claim
28 words
The method according to claim 5 wherein the composition has a pH from about 4 to about 5 and includes ZnSO 4 .7H 2 O and sodium ascorbate.
Claim 9
Dependent Claim
27 words
The method according to claim 6 wherein the ratio of the ZnSO 4 .7H 2 O to the sodium ascorbate is substantially 1 to 1 by weight.
Claim 10
Independent Claim
53 words
A method for treating pregnancy gingivitis comprising topically administering to oral tissues a therapeutically effective amount of a composition consisting essentially of about 0.5 to about 2.0 percent by weight/volume of a pharmaceutically acceptable, water soluble zinc salt and about 0.5 to about 2.0 percent by weight/volume of ascorbic acid or sodium ascorbate.
Claim 11
Independent Claim
53 words
A method for treating pregnancy gingivitis comprising topically administering to oral tissues a therapeutically effective amount of a composition consisting essentially of about 0.5 to about 2.0 percent by weight/volume of a pharmaceutically acceptable, water soluble zinc salt and about 0.5 to about 2.0 percent by weight/volume of ascorbic acid or sodium ascorbate.
Claim 12
Independent Claim
54 words
A method for treating oral canker sores comprising topically administering to oral tissues a therapeutically effective amount of a composition consisting essentially of about 0.5 to about 2.0 percent by weight/volume of a pharmaceutically acceptable, water soluble zinc salt and about 0.5 to about 2.0 percent by weight/volume of ascorbic acid or sodium ascorbate.
Claim 13
Independent Claim
54 words
A method for treating oral canker sores comprising topically administering to oral tissues a therapeutically effective amount of a composition consisting essentially of about 0.5 to about 2.0 percent by weight/volume of a pharmaceutically acceptable, water soluble zinc salt and about 0.5 to about 2.0 percent by weight/volume of ascorbic acid or sodium ascorbate.
Claim 14
Independent Claim
53 words
A method for treating idopathic hypogeusia comprising topically administering to oral tissues a therapeutically effective amount of a composition consisting essentially of about 0.5 to about 2.0 percent by weight/volume of a pharmaceutically acceptable, water soluble zinc salt and about 0.5 to about 2.0 percent by weight/volume of ascorbic acid or sodium ascorbate.
Claim 15
Independent Claim
53 words
A method for treating idopathic hypogeusia comprising topically administering to oral tissues a therapeutically effective amount of a composition consisting essentially of about 0.5 to about 2.0 percent by weight/volume of a pharmaceutically acceptable, water soluble zinc salt and about 0.5 to about 2.0 percent by weight/volume of ascorbic acid or sodium ascorbate.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1983-10-21 | 1984-04-21 | 1984-10-21 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1987-10-21 | 1988-04-21 | 1988-10-21 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1991-10-21 | 1992-04-21 | 1992-10-21 | $7700.00 | Window Closed / Lapsed |