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US4227003A
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Bromo-A-23187 derivatives
Assignee: Eli Lilly and Co
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Filing: 1978-10-11
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Granted: 1980-10-07
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Expires: 1998-10-11
Abstract
Abstract Bromo-A-23187 derivatives, prepared by reaction of antibiotic A-23187 with pyridinium hydrobromide perbromide and salts thereof, which are (1) useful biochemical tools for the study of transport of ions in cellular systems, and (2) useful chemical tools for removal and recovery of ions.
Inventors
- 👤 Manuel Debono
- 👤 R. Michael Molloy
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-05 15:19
CPC Classifications
C; C07; C07D; C07D493/00; C07D493/02; C07D493/10; C07F; C07F3/00; C07F3/02
Claims Analysis
Total Claims: 6
Claim 1
Independent Claim
24 words
A compound selected from a group consisting of compounds having the following formulas: ##STR3## and the Pharmaceutically acceptable cationic salts of (1) and (2).
Claim 2
Dependent Claim
24 words
A compound selected from a group consisting of compounds having the following formulas: ##STR3## and the Pharmaceutically acceptable cationic salts of (1) and (2).
Claim 3
Dependent Claim
16 words
A compound of claim 1 having formula (1) and the pharmaceutically acceptable cationic salts of (1).
Claim 4
Dependent Claim
10 words
The compound of claim 2 which is 23-bromo-A-23187 magnesium salt.
Claim 5
Dependent Claim
16 words
A compound of claim 1 having formula (2) and the pharmaceutically acceptable cationic salts of (2).
Claim 6
Dependent Claim
10 words
The compound of claim 4 which is 23,24-dibromo-A-23187 magnesium salt.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1983-10-07 | 1984-04-07 | 1984-10-07 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1987-10-07 | 1988-04-07 | 1988-10-07 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1991-10-07 | 1992-04-07 | 1992-10-07 | $7700.00 | Window Closed / Lapsed |