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US4226850A
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Methods for controlling perspiration
Assignee: Meda Pharmaceuticals Inc
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Filing: 1976-11-12
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Granted: 1980-10-07
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Expires: 1996-11-12
Abstract
Abstract Antiperspirant compositions containing antihistamines, such as diphenhydramine hydrochloride, alone or in combination with astringent metallic salts, as the active agent effective for retarding or inhibiting perspiration when topically applied to the human skin. Method for controlling or preventing perspiration in humans.
Inventors
- 👤 Elias W. Packman
- 👤 Ruth Jeffkin
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-02 03:19
CPC Classifications
A; A61; A61K; A61K8/00; A61K8/18; A61K8/30; A61K8/49; A61K8/4906; A61K8/4926; A61K8/40; A61K8/41; A61Q; A61Q15/00
Claims Analysis
Total Claims: 18
Claim 1
Independent Claim
62 words
A method of controlling perspiration which comprises administering topically an antiperspirant composition to a human in need thereof, the composition comprising an antihistamine selected from the group consisting of an ethanolamine, an ethylenediamine, an alkylamine, a phenothiazine and a piperazine, or a physiologically acceptable salt thereof, and a pharmaceutically acceptable carrier, the antihistamine being in an amount effective to control the perspiration.
Claim 2
Independent Claim
62 words
A method of controlling perspiration which comprises administering topically an antiperspirant composition to a human in need thereof, the composition comprising an antihistamine selected from the group consisting of an ethanolamine, an ethylenediamine, an alkylamine, a phenothiazine and a piperazine, or a physiologically acceptable salt thereof, and a pharmaceutically acceptable carrier, the antihistamine being in an amount effective to control the perspiration.
Claim 3
Dependent Claim
17 words
The method of claim 1 wherein the administration is to the axillary area of the human body.
Claim 4
Dependent Claim
10 words
The method of claim 1 which comprises repeating the administration.
Claim 5
Dependent Claim
19 words
The method of claim 3 wherein the decrease in perspiration is greater after the subsequent than the first administration.
Claim 6
Dependent Claim
28 words
The method of claim 3 wherein the antihistamine is present in said antiperspirant composition in an amount in the range of about 0.01% to about 10% by weight.
Claim 7
Dependent Claim
28 words
The method of claim 5 wherein the antihistamine is present in said antiperspirant composition in an amount in the range of about 0.5% to about 5% by weight.
Claim 8
Dependent Claim
27 words
The method of claim 6 wherein the antihistamine is present in said antiperspirant composition in an amount in the range of about 0.5% to 1% by weight.
Claim 9
Dependent Claim
19 words
The method of claim 1 wherein the antihistamine is selected from the group consisting of diphenhydramine, chlorpheniramine, and tripelennamine.
Claim 10
Dependent Claim
10 words
The method of claim 8 wherein the antihistamine is chlorpheniramine.
Claim 11
Dependent Claim
10 words
The method of claim 8 wherein the antihistamine is diphenhydramine.
Claim 12
Dependent Claim
10 words
The method of claim 8 wherein the antihistamine is tripelennamine.
Claim 13
Dependent Claim
16 words
The method of claim 8 wherein there is administered a physiologically acceptable salt of the antihistamine.
Claim 14
Dependent Claim
14 words
The method of claim 12 wherein the salt is the hydrochloride or maleate salt.
Claim 15
Dependent Claim
11 words
The method of claim 1 wherein the administration is by spray.
Claim 16
Dependent Claim
44 words
The method of claim 1 wherein the administration is to a localized area of the body which has apocrine sweat glands which are primarily responsive to emotional stimuli or muscular activity, and causing the inhibition of sweat secretion and of the offensive sweat odor.
Claim 17
Dependent Claim
20 words
The method of claim 1 wherein the composition is applied topically to an area not exposed to an external immunogen.
Claim 18
Dependent Claim
18 words
The process of claim 1 wherein the application is to the axillae or to the sole of feet.
References Cited (Backward Citations)
US3624200A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1983-10-07 | 1984-04-07 | 1984-10-07 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1987-10-07 | 1988-04-07 | 1988-10-07 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1991-10-07 | 1992-04-07 | 1992-10-07 | $7700.00 | Window Closed / Lapsed |