Patent US4220641A successfully refreshed from Google Patents.
US4220641A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Organic compounds
Assignee: Fidelity Union Bank
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Filing: 1978-05-04
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Granted: 1980-09-02
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Expires: 1998-05-04
Abstract
Abstract The present invention relates to cyclosporin derivatives, especially compounds of formula I ##STR1## wherein A is ##STR2## useful as anti-arthritic agents.
Inventors
- 👤 Rene P. Traber
- 👤 Max Kuhn
- 👤 Hans Hofmann
- 👤 Eugen Harri
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-25 06:38
CPC Classifications
C; C07; C07K; C07K7/00; C07K7/64; C07K7/645; A; A61; A61P; A61P29/00; A61P37/00; A61P37/02; A61P37/06; A61K; A61K38/00; Y; Y10; Y10S; Y10S435/00; Y10S435/8215; Y10S435/911; Y10S435/945; Y10S930/00; Y10S930/01; Y10S930/19; Y10S930/27
Claims Analysis
Total Claims: 11
Claim 1
Independent Claim
11 words
A compound closen from cyclosporin D, dihydrocyclosporin D or isocyclosporin D.
Claim 2
Dependent Claim
11 words
A compound closen from cyclosporin D, dihydrocyclosporin D or isocyclosporin D.
Claim 3
Dependent Claim
9 words
The compound of claim 1 which is cyclosporin D.
Claim 4
Dependent Claim
9 words
The compound of claim 1 which is dihydrocyclosporin D.
Claim 5
Dependent Claim
9 words
The compound of claim 1 which is isocyclosporin D.
Claim 6
Dependent Claim
30 words
A pharmaceutical composition useful in treating chronic inflammations or immunosuppressant disorders comprising a therapeutically effective amount of a compound of claim 1 in association with a pharmaceutical carrier or diluent.
Claim 7
Dependent Claim
14 words
The pharmaceutical composition according to claim 5 in which the compound is isocyclosporin D.
Claim 8
Dependent Claim
32 words
A method of treating chronic inflammations or immuno-suppressive disorders in animals, which comprises administering a therapeutically effective amount of a compound of claim 1 to an animal in need of such treatment.
Claim 9
Dependent Claim
12 words
The method of claim 7 in which the compound is isocyclosporin D.
Claim 10
Dependent Claim
19 words
A method according to claim 8 in which from 50 to 900 milligrams of the compound are administered daily.
Claim 11
Dependent Claim
23 words
A method according to claim 8 in which from 15 to 450 milligrams of the compound are administered orally in unit dosage form.
References Cited (Backward Citations)
No citation records indexed.
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1983-09-02 | 1984-03-03 | 1984-09-02 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1987-09-02 | 1988-03-03 | 1988-09-02 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1991-09-02 | 1992-03-03 | 1992-09-02 | $7700.00 | Window Closed / Lapsed |