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US4218782A
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US
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Heart valve prosthesis and method for the production thereof
Assignee: BIOCOATING ANPARTSSELSKAB
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Filing: 1978-05-19
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Granted: 1980-08-26
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Expires: 1998-05-19
Abstract
Abstract A flexible non-stented heart valve prosthesis made from a flat piece of a stabilized biological membrane. The membrane is folded along one or more folding lines and attached to a flat flexible non-biological base material so that one or more leaflets are formed. Preferably the membrane is pericardium and is attached by machine stitching to a woven polymeric base material. Different valve types including ventricular outflow patches and three-leaflet valves such as aortic valves and methods for their production are described. The aortic valve is preferably made from three separate leaflets provided with narrow base materials serving as attachment margins which are stitched together in a manner to form a three-leaflet valve.
Inventors
- 👤 Inge H. Rygg
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 14:49
CPC Classifications
A; A61; A61F; A61F2/00; A61F2/02; A61F2/24; A61F2/2412; A61F2/2415
Claims Analysis
Total Claims: 23
Claim 1
Independent Claim
43 words
A heart valve prosthesis made from a flat strip piece of a stabilized biological membrane which is folded along at least one folding line to form opposed layers and attached to a flat flexible non-biological base material to form at least one leaflet.
Claim 2
Dependent Claim
43 words
A heart valve prosthesis made from a flat strip piece of a stabilized biological membrane which is folded along at least one folding line to form opposed layers and attached to a flat flexible non-biological base material to form at least one leaflet.
Claim 3
Dependent Claim
15 words
The heart valve prosthesis according to claim 1, wherein the strip is attached by stitching.
Claim 4
Dependent Claim
16 words
A heart valve prosthesis according to claim 2, wherein the strip is attached by machine stitching.
Claim 5
Dependent Claim
30 words
The heart valve prosthesis according to claim 1, wherein a biological membrane having on one side a mesothelial layer, is attached so that the non-mesothelial side faces the base material.
Claim 6
Dependent Claim
18 words
The heart valve prosthesis according to claim 1, wherein the non-biological base material is a flexible polymeric material.
Claim 7
Dependent Claim
16 words
The heart valve prosthesis according to claim 5, wherein the polymeric material is a woven material.
Claim 8
Dependent Claim
15 words
The heart valve prosthesis according to claim 1, wherein the biological membrane is porcine pericardium.
Claim 9
Dependent Claim
27 words
The heart valve prosthesis according to claim 1, wherein the biological membrane is provided with a reinforcement at least in the region forming the leaflet or leaflets.
Claim 10
Dependent Claim
24 words
The heart valve prosthesis according to claim 8, wherein said reinforcement is provided by impregnating the biological membrane with a physiologically compatible polymeric material.
Claim 11
Dependent Claim
20 words
The heart valve prosthesis according to claim 4, wherein the biological membrane is reinforced by impregnating from the non-mesothelial side.
Claim 12
Dependent Claim
30 words
The heart valve prosthesis according to claim 8, wherein said reinforcement is provided by inserting a polymeric material, between the two layers of biological membrane forming the leaflet or leaflets.
Claim 13
Dependent Claim
19 words
The heart valve prosthesis according to claim 11, wherein said reinforcing polymeric material is in the form of filaments.
Claim 14
Dependent Claim
33 words
The heart valve prosthesis according to claim 1, wherein at least in the region forming the leaflets the strip is stretched in the folding direction prior to the placing on the base material.
Claim 15
Dependent Claim
43 words
The heart valve prosthesis according to claim 1, wherein the strip of biological membrane after the folding and the formation of at least one leaflet is shaped to a tube, the longitudinal axis of which is disposed substantially perpendicularly to the folding lines.
Claim 16
Dependent Claim
84 words
A heart valve prosthesis according to claim 1 for use as an aortic valve prosthesis comprising three tongue-shaped leaflets each of which being formed by folding a strip of a biological membrane along a folding line, attaching on either side a narrow tape-shaped base material of a flexible nonbiological material serving as attachment margins, removing the portion of the membrane located outside the attachment margins and stitching together said leaflets in pairs along a section of the attachment margins to form a three-leaflet valve.
Claim 17
Independent Claim
47 words
A method of producing a heart valve prosthesis comprising the steps of folding a flat strip piece of biological membrane along at least one folding line to form opposed layers and stitching the strip on a flat flexible non-biological base material to form at least one leaflet.
Claim 18
Independent Claim
47 words
A method of producing a heart valve prosthesis comprising the steps of folding a flat strip piece of biological membrane along at least one folding line to form opposed layers and stitching the strip on a flat flexible non-biological base material to form at least one leaflet.
Claim 19
Dependent Claim
54 words
The method according to claim 16 comprising the steps of folding the strip along two parallel folding lines, stitching the strip on the base material, forming three leaflets and further stitching the marginal regions together in order to form a tube the longitudinal axis of which is disposed substantially perpendicularly to the folding lines.
Claim 20
Independent Claim
74 words
A method of producing an aortic valve prosthesis comprising the steps of folding a strip of a biological membrane along a folding line, stitching a tongue-shaped attachment margin of a tape-shaped flexible non-biological material to either side of the membrane, removing the excess portion of the membrane, stitching the obtained tongue-shaped leaflet together with two leaflets produced in the same manner along a section of the respective attachment margins to form a three-leaflet valve.
Claim 21
Independent Claim
74 words
A method of producing an aortic valve prosthesis comprising the steps of folding a strip of a biological membrane along a folding line, stitching a tongue-shaped attachment margin of a tape-shaped flexible non-biological material to either side of the membrane, removing the excess portion of the membrane, stitching the obtained tongue-shaped leaflet together with two leaflets produced in the same manner along a section of the respective attachment margins to form a three-leaflet valve.
Claim 22
Dependent Claim
16 words
The heart valve prosthesis according to claim 5, wherein the polymeric material is a crocheted material.
Claim 23
Dependent Claim
15 words
The heart valve prosthesis according to claim 1, wherein the biological membrane is calf pericardium.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1983-08-26 | 1984-02-25 | 1984-08-26 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1987-08-26 | 1988-02-25 | 1988-08-26 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1991-08-26 | 1992-02-25 | 1992-08-26 | $7700.00 | Window Closed / Lapsed |