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US4215064A Expired / Lapsed US ⏱️ 0.0 years remaining

Phosphobetaines

Assignee: Johnson and Johnson
•
Filing: 1978-11-30
•
Granted: 1980-07-29
•
Expires: 1998-11-30
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Abstract

Abstract Phosphobetaine Compounds of the formula ##STR1## wherein A is selected from O - , OM and --O--Y--R+ B is selected from O - and OM - X - is an anion Z is an integer from 0 to 2 with the proviso that only one of A and B can be O - and Z is of a value necessary for charge balance and R is an amidoamine reactant moiety.

Inventors

  • 👤 Martin K. O. Lindemann
  • 👤 Raymond L. Mayhew
  • 👤 Anthony J. O'Lenick, Jr.
  • 👤 Robert J. Verdicchio

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-25 02:27
CPC Classifications
C; C11; C11D; C11D1/00; C11D1/88; C11D1/94; C07; C07F; C07F9/00; C07F9/02; C07F9/06; C07F9/08; C07F9/09; C07F9/091; C07F9/141; C07F9/1411; C07F9/547; C07F9/645; C07F9/6503; C07F9/6506; C07F9/6527; C07F9/6533; C07F9/655; C07F9/65502; C11D1/38; C11D1/62; C11D1/65; C11D1/886; Y; Y10; Y10S; Y10S516/00; Y10S516/01; Y10S516/06; Y10S516/07

Claims Analysis

Total Claims: 20
Claim 1
Independent Claim 365 words
Phosphobetaine compounds of the formula wherein A is selected from O - , OM, and --O--Y--R + B is selected from O - and OM' X - is an anion z is an integer from 0 to 2 with the proviso that only one of A and B can be O - and z is of a value necessary for charge balance; R is an amidoamine reactant moiety of the formula ##STR113## wherein R 1 is alkyl, alkenyl, alkoxy, or hydroxyalkyl of from 5 to 22 carbon atoms each, or aryl or alkaryl of up to 20 carbon atoms, R 2 is hydrogen or alkyl, hydroxyalkyl or alkenyl of up to 6 carbon atoms each or cycloalkyl of up to 6 carbon atoms, preferably of from 2 to 5 carbon atoms, or polyoxyalkalene of up to 10 carbon atoms, R 3 and R 4 , which may be the same or different, are selected from alkyl, hydroxyalkyl, carboxyalkyl of up to 6 carbon atoms in each alkyl moiety, and polyoxyalkylene of up to 10 carbon atoms; in addition, R 3 and R 4 taken together with the nitrogen to which they are attached, may represent an N-heterocycle, e.g., a morpholino structure, in which the Y radical is bonded to a ring atom of said N-heterocycle other than the nitrogen of the R moiety; n is an integer from 2 to 12; Y is alkylene, optionally interrupted by up to 3 oxygen atoms, of up to 12 carbon atoms, which alkylene chain may optionally be substituted with lower alkyl, alkoxy, hydroxy or hydroxyalkyl, e.g. of not more than 10 carbon atoms each; M and M', which may be the same or different, are (a) hydrogen, (b) an organic radical selected from alkyl or hydroxyalkyl of up to 6 carbon atoms, polyhydroxyalkyl of up to 10 carbon atoms, glyceryl, cycloalkyl of up to 6 carbon atoms, aryl or arylalkyl of up to 10 carbon atoms, or (c) a salt radical selected from alkali metals, alkaline earth metals, and mono-, di-, or tri-ethanolamine, provided that when either M or M' is an organic radical (b), the other M and M' must be hydrogen or a salt radical (c).
Claim 2
Dependent Claim 365 words
Phosphobetaine compounds of the formula wherein A is selected from O - , OM, and --O--Y--R + B is selected from O - and OM' X - is an anion z is an integer from 0 to 2 with the proviso that only one of A and B can be O - and z is of a value necessary for charge balance; R is an amidoamine reactant moiety of the formula ##STR113## wherein R 1 is alkyl, alkenyl, alkoxy, or hydroxyalkyl of from 5 to 22 carbon atoms each, or aryl or alkaryl of up to 20 carbon atoms, R 2 is hydrogen or alkyl, hydroxyalkyl or alkenyl of up to 6 carbon atoms each or cycloalkyl of up to 6 carbon atoms, preferably of from 2 to 5 carbon atoms, or polyoxyalkalene of up to 10 carbon atoms, R 3 and R 4 , which may be the same or different, are selected from alkyl, hydroxyalkyl, carboxyalkyl of up to 6 carbon atoms in each alkyl moiety, and polyoxyalkylene of up to 10 carbon atoms; in addition, R 3 and R 4 taken together with the nitrogen to which they are attached, may represent an N-heterocycle, e.g., a morpholino structure, in which the Y radical is bonded to a ring atom of said N-heterocycle other than the nitrogen of the R moiety; n is an integer from 2 to 12; Y is alkylene, optionally interrupted by up to 3 oxygen atoms, of up to 12 carbon atoms, which alkylene chain may optionally be substituted with lower alkyl, alkoxy, hydroxy or hydroxyalkyl, e.g. of not more than 10 carbon atoms each; M and M', which may be the same or different, are (a) hydrogen, (b) an organic radical selected from alkyl or hydroxyalkyl of up to 6 carbon atoms, polyhydroxyalkyl of up to 10 carbon atoms, glyceryl, cycloalkyl of up to 6 carbon atoms, aryl or arylalkyl of up to 10 carbon atoms, or (c) a salt radical selected from alkali metals, alkaline earth metals, and mono-, di-, or tri-ethanolamine, provided that when either M or M' is an organic radical (b), the other M and M' must be hydrogen or a salt radical (c).
Claim 3
Dependent Claim 22 words
Phosphobetaine compound as claimed in claim 1, of the formula ##STR114## wherein the R, Y amd M radicals are defined as before.
Claim 4
Dependent Claim 23 words
Phosphobetaine as claimed in claim 1, of the formula ##STR115## wherein the R, Y, M, M' and X radicals are defined as before.
Claim 5
Dependent Claim 21 words
Phosphobetaine as claimed in claim 1, of the formula ##STR116## wherein the R, Y and X radicals are defined as before.
Claim 6
Dependent Claim 177 words
Phosphobetaine compounds as claimed in claim 2, wherein R is an amidoamine reactant moiety of the formula ##STR117## wherein R 1 is alkyl, alkenyl, alkoxy, or hydroxyalkyl of from 5 to 22 carbon atoms each, or aryl or alkaryl of up to 20 carbon atoms, R 2 is hydrogen or alkyl, hydroxyalkyl or alkenyl of up to 6 carbon atoms each or cycloalkyl of up to 6 carbon atoms, preferably of from 2 to 5 carbon atoms, or polyoxyalkalene of up to 10 carbon atoms, R 3 and R 4 , which may be the same or different, are selected from alkyl, hydroxyalkyl, carboxyalkyl of up to 6 carbon atoms in each alkyl moiety, and polyoxyalkylene of up to 10 carbon atoms; in addition, R 3 and R 4 taken together with the nitrogen to which they are attached, may represent an N-heterocycle, e.g., a morpholino structure, in which the Y radical is bonded to a ring atom of said N-heterocycle other than the nitrogen of the R moiety; n is an integer from 2 to 12.
Claim 7
Dependent Claim 169 words
Phosphobetaine compound as claimed in claim 3, wherein R is ##STR118## wherein R 1 is alkyl, alkenyl, alkoxy, or hydroxyalkyl of from 5 to 22 carbon atoms each, or aryl or alkaryl of up to 20 carbon atoms, R 2 is hydrogen or alkyl, hydroxyalkyl or alkenyl of up to 6 carbon atoms each or cycloalkyl of up to 6 carbon atoms, preferably of from 2 to 5 carbon atoms, or polyoxyalkalene of up to 10 carbon atoms, R 3 and R 4 , which may be the same or different, are selected from alkyl, hydroxyalkyl, carboxyalkyl of up to 6 carbon atoms in each alkyl moiety, and polyoxyalkylene of up to 10 carbon atoms; in addition, R 3 and R 4 taken together with the nitrogen to which they are attached, may represent an N-heterocycle, e.g., a morpholino structure, in which the Y radical is bonded to a ring atom of said N-heterocycle other than the nitrogen of the R moiety; n is an integer from 2 12.
Claim 8
Dependent Claim 170 words
Phosphobetaine compound as claimed in claim 4, wherein R is ##STR119## wherein R 1 is alkyl, alkenyl, alkoxy, or hydroxyalkyl of from 5 to 22 carbon atoms each, or aryl or alkaryl of up to 20 carbon atoms, R 2 is hydrogen or alkyl, hydroxyalkyl or alkenyl of up to 6 carbon atoms each or cycloalkyl of up to 6 carbon atoms, preferably of from 2 to 5 carbon atoms, or polyoxyalkalene of up to 10 carbon atoms, R 3 and R 4 , which may be the same or different, are selected from alkyl, hydroxyalkyl, carboxyalkyl of up to 6 carbon atoms in each alkyl moiety, and polyoxyalkylene of up to 10 carbon atoms; in addition, R 3 and R 4 taken together with the nitrogen to which they are attached, may represent an N-heterocycle, e.g., a morpholino structure, in which the Y radical is bonded to a ring atom of said N-heterocycle other than the nitrogen of the R moiety; n is an integer from 2 to 12.
Claim 9
Dependent Claim 11 words
Phosphobetaine compound as claimed in claim 2, wherein M is hydrogen.
Claim 10
Dependent Claim 48 words
Phosphobetaine compound as claimed in claim 2, wherein M is an organic radical selected from alkyl or hydroxyalkyl of up to 6 carbon atoms, polyhydroxyalkyl of up to 10 carbon atoms, glyceryl, cycloalkyl of up to 6 carbon atoms, aryl or arylalkyl of up to 10 carbon atoms.
Claim 11
Dependent Claim 28 words
Phosphobetaine compound as claimed in claim 2, wherein M is a salt radical selected from alkali metals, alkaline earth metals, alkaline earth metals and mono-, di-, or tri-ethanolamine.
Claim 12
Dependent Claim 15 words
Phosphobetaine compound as claimed in claim 3, wherein one of M and M' is hydrogen.
Claim 13
Dependent Claim 52 words
Phosphobetaine compound as claimed in claim 3, wherein one of M and M' is an organic radical selected from alkyl or hydroxyalkyl of up to 6 carbon atoms, polyhydroxyalkyl of up to 10 carbon atoms, glyceryl, cycloalkyl of up to 6 carbon atoms, aryl or arylalkyl of up to 10 carbon atoms.
Claim 14
Dependent Claim 32 words
Phosphobetaine compound as claimed in claim 3, wherein one of M and M' is a salt radical selected from alkali metals, alkaline earth metals alkaline earth metals and mono-, di-, or tri-ethanolamine.
Claim 15
Dependent Claim 16 words
Phosphobetaine compound as claimed in claim 1, wherein said compound is lauric myristic amido 3-hydroxypropyl phosphobetaine.
Claim 16
Dependent Claim 15 words
Phosphobetaine compound as claimed in claim 1, wherein said compound is cocamido disodium 3-hydroxypropyl phosphobetaine.
Claim 17
Dependent Claim 17 words
Phosphobetaine compound as claimed in claim 1, wherein said compound is lauric myristic amido monosodium 3-hydroxypropyl phosphobetaine.
Claim 18
Dependent Claim 17 words
Phosphobetaine compound as claimed in claim 1, wherein said compound is lauric myristic amido disodium 3-hydroxypropyl phosphobetaine.
Claim 19
Dependent Claim 16 words
Phosphobetaine compound as claimed in claim 1, wherein said compound is lauric myristic amido glyceryl phosphobetaine.
Claim 20
Dependent Claim 18 words
Phosphobetaine compound as claimed in claim 1, wherein said compound is lauric myristic amido carboxy disodium 3-hydroxypropyl phosphobetaine.

References Cited (Backward Citations)

US3856893A Cited
US3962418A Cited
US3928509A Cited
US3950417A Cited
US4181634A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1983-07-29 1984-01-28 1984-07-29 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1987-07-29 1988-01-28 1988-07-29 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1991-07-29 1992-01-28 1992-07-29 $7700.00 Window Closed / Lapsed

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