Patent US4207234A successfully refreshed from Google Patents.
US4207234A
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US
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4-Unsubstituted azetidinone derivatives and process for preparation thereof
Assignee: Astellas Pharma Inc
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Filing: 1977-12-07
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Granted: 1980-06-10
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Expires: 1997-12-07
Abstract
Abstract New antimicrobial azetidinone derivatives and their salt of the formula: ##STR1## wherein R 1 is amino or acylamino, and A is selected from a variety of groups.
Inventors
- 👤 Takashi Kamiya
- 👤 Yoshihisa Saito
- 👤 Masashi Hashimoto
- 👤 Osamu Nakaguti
- 👤 Teruo Oku
- 👤 Youichi Shiokawa
- 👤 Takao Takaya
- 👤 Tadaaki Komori
- 👤 Tsutomu Teraji
- 👤 Keiji Hemmi
- 👤 Hisashi Takasugi
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-04 16:24
CPC Classifications
C; C07; C07D; C07D205/00; C07D205/02; C07D205/06; C07D205/08; C07D205/085; C07D473/00
Claims Analysis
Total Claims: 5
Claim 1
Independent Claim
120 words
An azetidinone compound substantially free of other azetidinones, and having the formula: ##STR611## wherein: R 1 is amino or acylamino excepting 2-[4-(3-amino-3-carboxypropoxy)phenyl]-2-hydroxyiminoacetamido, the acyl moiety of the acylamino group consisting of a carboxylic acid acyl or a benzenesulfonyl; R Yc is hydrogen, amino, nitro, halogen, alkoxy containing up to 6 carbon atoms, or alkylthio containing up to 6 carbon atoms; R Yd is hydrogen, hydroxy, alkyl containing up to 6 carbon atoms, alkylthio containing up to 6 carbon atoms, or benzyloxy; R Ye is hydrogen, halogen, alkoxy containing up to 6 carbon atoms, or alkylthio containing up to 6 carbon atoms; and R za is carboxy, a pharmaceutically acceptable salt or as ester thereof, excepting 2-(4 -hydroxyphenyl)-2-(2-oxo-3-(2-hydroxyimino-2-(4-hydroxyphenyl) acetamido-1-azetidinyl) acetic acid.
Claim 2
Dependent Claim
120 words
An azetidinone compound substantially free of other azetidinones, and having the formula: ##STR611## wherein: R 1 is amino or acylamino excepting 2-[4-(3-amino-3-carboxypropoxy)phenyl]-2-hydroxyiminoacetamido, the acyl moiety of the acylamino group consisting of a carboxylic acid acyl or a benzenesulfonyl; R Yc is hydrogen, amino, nitro, halogen, alkoxy containing up to 6 carbon atoms, or alkylthio containing up to 6 carbon atoms; R Yd is hydrogen, hydroxy, alkyl containing up to 6 carbon atoms, alkylthio containing up to 6 carbon atoms, or benzyloxy; R Ye is hydrogen, halogen, alkoxy containing up to 6 carbon atoms, or alkylthio containing up to 6 carbon atoms; and R za is carboxy, a pharmaceutically acceptable salt or as ester thereof, excepting 2-(4 -hydroxyphenyl)-2-(2-oxo-3-(2-hydroxyimino-2-(4-hydroxyphenyl) acetamido-1-azetidinyl) acetic acid.
Claim 3
Dependent Claim
34 words
A. Compound according to claim 1, wherein R d1 is acylamino as defined, and R Y is hydrogen, hydroxy, alkyl containing up to 6 carbon atoms, or alkylthio containing up to 6 carbon atoms.
Claim 4
Dependent Claim
20 words
A compound according to claim 1, wherein R 1 and R Ye are each hydrogen, and R Yd is hydroxy.
Claim 5
Dependent Claim
24 words
A compound according to claim 1, wherein R 1 is amino, R Yc and R Ye are each hydrogen, and R Yd is hydroxy.
References Cited (Backward Citations)
US2923977A
Cited
DE2529941A1
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1983-06-10 | 1983-12-10 | 1984-06-10 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1987-06-10 | 1987-12-10 | 1988-06-10 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1991-06-10 | 1991-12-10 | 1992-06-10 | $7700.00 | Window Closed / Lapsed |