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US4206221A
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Cephalomannine and its use in treating leukemic tumors
Assignee: United States Department of Agriculture
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Filing: 1979-01-03
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Granted: 1980-06-03
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Expires: 1999-01-03
Abstract
Abstract A novel alkaloid named "cephalomannine" has been produced from the tissue of plants belonging to the group commonly known as taxads and has proven to be effective in causing the remission of leukemic tumors in mice treated therewith. Cephalomannine is characterized by the following structural formula: <IMAGE>
Inventors
- 👤 Roger W. Miller
- 👤 Richard G. Powell
- 👤 Cecil R. Smith, Jr.
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-28 10:40
CPC Classifications
C; C07; C07D; C07D305/00; C07D305/14
Claims Analysis
Total Claims: 7
Claim 1
Independent Claim
13 words
A substantially pure chemotherapeutically active alkaloid compound cephalomannine having the following structure: ##STR6##
Claim 2
Dependent Claim
13 words
A substantially pure chemotherapeutically active alkaloid compound cephalomannine having the following structure: ##STR6##
Claim 3
Dependent Claim
26 words
A chemotherapeutic composition suitable for the remission of leukemic tumors of the strain P388 comprising an injection vehicle and an effective amount of substantially pure cephalomannine.
Claim 4
Dependent Claim
26 words
A chemotherapeutic composition suitable for the remission of leukemic tumors of the strain P388 comprising an injection vehicle and an effective amount of substantially pure cephalomannine.
Claim 5
Dependent Claim
14 words
The chemotherapeutic composition described in claim 2 wherein said injection vehicle is a liquid.
Claim 6
Independent Claim
33 words
A method of treating animals for remission of leukemia of the strain P388 comprising administering to said animals a chemotherapeutic composition comprising an injection vehicle and an effective amount of substantially pure cephalomannine.
Claim 7
Independent Claim
33 words
A method of treating animals for remission of leukemia of the strain P388 comprising administering to said animals a chemotherapeutic composition comprising an injection vehicle and an effective amount of substantially pure cephalomannine.
References Cited (Backward Citations)
No citation records indexed.
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1983-06-03 | 1983-12-03 | 1984-06-03 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1987-06-03 | 1987-12-03 | 1988-06-03 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1991-06-03 | 1991-12-03 | 1992-06-03 | $7700.00 | Window Closed / Lapsed |