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US4206221A Expired / Lapsed US ⏱️ 0.0 years remaining

Cephalomannine and its use in treating leukemic tumors

Assignee: United States Department of Agriculture
•
Filing: 1979-01-03
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Granted: 1980-06-03
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Expires: 1999-01-03
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Abstract

Abstract A novel alkaloid named "cephalomannine" has been produced from the tissue of plants belonging to the group commonly known as taxads and has proven to be effective in causing the remission of leukemic tumors in mice treated therewith. Cephalomannine is characterized by the following structural formula: <IMAGE>

Inventors

  • 👤 Roger W. Miller
  • 👤 Richard G. Powell
  • 👤 Cecil R. Smith, Jr.

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-28 00:40
CPC Classifications
C; C07; C07D; C07D305/00; C07D305/14

Claims Analysis

Total Claims: 7
Claim 1
Independent Claim 13 words
A substantially pure chemotherapeutically active alkaloid compound cephalomannine having the following structure: ##STR6##
Claim 2
Dependent Claim 13 words
A substantially pure chemotherapeutically active alkaloid compound cephalomannine having the following structure: ##STR6##
Claim 3
Dependent Claim 26 words
A chemotherapeutic composition suitable for the remission of leukemic tumors of the strain P388 comprising an injection vehicle and an effective amount of substantially pure cephalomannine.
Claim 4
Dependent Claim 26 words
A chemotherapeutic composition suitable for the remission of leukemic tumors of the strain P388 comprising an injection vehicle and an effective amount of substantially pure cephalomannine.
Claim 5
Dependent Claim 14 words
The chemotherapeutic composition described in claim 2 wherein said injection vehicle is a liquid.
Claim 6
Independent Claim 33 words
A method of treating animals for remission of leukemia of the strain P388 comprising administering to said animals a chemotherapeutic composition comprising an injection vehicle and an effective amount of substantially pure cephalomannine.
Claim 7
Independent Claim 33 words
A method of treating animals for remission of leukemia of the strain P388 comprising administering to said animals a chemotherapeutic composition comprising an injection vehicle and an effective amount of substantially pure cephalomannine.

References Cited (Backward Citations)

No citation records indexed.

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1983-06-03 1983-12-03 1984-06-03 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1987-06-03 1987-12-03 1988-06-03 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1991-06-03 1991-12-03 1992-06-03 $7700.00 Window Closed / Lapsed

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