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US4204537A Expired / Lapsed US ⏱️ 0.0 years remaining

Process for pheresis procedure and disposable plasma

Assignee: Haemonetics Corp
•
Filing: 1977-06-27
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Granted: 1980-05-27
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Expires: 1997-06-27
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Abstract

Abstract A pheresis process and apparatus for carrying it out. Blood from a donor is transferred to a pheresis bowl formed to have a red cell reservoir and a plasma reservoir in fluid communication through plasma ducts. The pheresis bowl is adapted for centrifuging to separate the red cells and plasma. This separation is accomplished simultaneously with the withdrawal of blood from the donor. At the end of the withdrawal the red cells are returned to the donor. The connection with the donor is thus continuously maintained during the entire procedure. The process is safe, fast and economical.

Inventors

  • 👤 Allen Latham, Jr.

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-23 16:09
CPC Classifications
B; B04; B04B; B04B5/00; B04B5/04; B04B5/0442

Claims Analysis

Total Claims: 6
Claim 1
Independent Claim 173 words
A blood pheresis process, comprising the steps of: (a) withdrawing whole blood from a donor through phlebotomy needle means connected to said donor and simultaneously admixing anticoagulant therewith; (b) introducing the resulting anticoagulated whole blood by way of a fluid conduit system into the bottom of a first reservoir while said reservoir is rotating about an axis of rotation; (c) rotating said first reservoir at centrifuging speed thereby to separate the plasma in said blood from the red cells; (d) transferring the resulting separated plasma to a second reservoir affixed coaxially to said first reservoir and rotating about said axis of rotation therewith; (e) stopping said rotating so that the red cells settle to the bottom of the first reservoir; (f) returning said red cells to said donor through said fluid conduit system, the connection between said donor, said fluid conduit system, and said first reservoir being maintained throughout steps (a)-(f); and (g) separating said second reservoir from said first reservoir in a manner to aseptically seal said plasma within said second reservoir.
Claim 2
Dependent Claim 173 words
A blood pheresis process, comprising the steps of: (a) withdrawing whole blood from a donor through phlebotomy needle means connected to said donor and simultaneously admixing anticoagulant therewith; (b) introducing the resulting anticoagulated whole blood by way of a fluid conduit system into the bottom of a first reservoir while said reservoir is rotating about an axis of rotation; (c) rotating said first reservoir at centrifuging speed thereby to separate the plasma in said blood from the red cells; (d) transferring the resulting separated plasma to a second reservoir affixed coaxially to said first reservoir and rotating about said axis of rotation therewith; (e) stopping said rotating so that the red cells settle to the bottom of the first reservoir; (f) returning said red cells to said donor through said fluid conduit system, the connection between said donor, said fluid conduit system, and said first reservoir being maintained throughout steps (a)-(f); and (g) separating said second reservoir from said first reservoir in a manner to aseptically seal said plasma within said second reservoir.
Claim 3
Dependent Claim 20 words
A blood pehresis process in accordance with claim 1 including the step of freezing said plasma in said second reservoir.
Claim 4
Dependent Claim 24 words
A blood pheresis process in accordance with claim 1 including the step of transferring said plasma in said second reservoir to a freezing bag.
Claim 5
Dependent Claim 174 words
A blood pheresis process, comprising the steps of: (a) withdrawing whole blood from a donor through phlebotomy needle means connected to said donor and simultaneously admixing anticoagulant therewith; (b) introducing the resulting anticoagulated whole blood by way of a fluid conduit system into the bottom of a first reservoir while said reservoir is rotating about an axis of rotation; (c) rotating said first reservoir at centrifuging speed thereby to separate the plasma in said blood from the red cells; (d) transferring the resulting separated plasma to a second reservoir affixed coaxially to said first reservoir and rotating about said axis of rotation therewith, the plasma being transferred to a second reservoir through ducts communicating with the tops of each of the first and second reservoirs; (e) stopping said rotating so that the red cells settle to the bottom of the first reservoir; and (f) returning said red cells to said donor through said fluid conduit system, the connection between said donor, said fluid conduit system, and said first reservoir being maintained throughout steps (a)-(f).
Claim 6
Dependent Claim 174 words
A blood pheresis process, comprising the steps of: (a) withdrawing whole blood from a donor through phlebotomy needle means connected to said donor and simultaneously admixing anticoagulant therewith; (b) introducing the resulting anticoagulated whole blood by way of a fluid conduit system into the bottom of a first reservoir while said reservoir is rotating about an axis of rotation; (c) rotating said first reservoir at centrifuging speed thereby to separate the plasma in said blood from the red cells; (d) transferring the resulting separated plasma to a second reservoir affixed coaxially to said first reservoir and rotating about said axis of rotation therewith, the plasma being transferred to a second reservoir through ducts communicating with the tops of each of the first and second reservoirs; (e) stopping said rotating so that the red cells settle to the bottom of the first reservoir; and (f) returning said red cells to said donor through said fluid conduit system, the connection between said donor, said fluid conduit system, and said first reservoir being maintained throughout steps (a)-(f).

References Cited (Backward Citations)

US1825721A Cited
US2906452A Cited
US3185154A Cited
US3655123A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1983-05-27 1983-11-26 1984-05-27 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1987-05-27 1987-11-26 1988-05-27 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1991-05-27 1991-11-26 1992-05-27 $7700.00 Window Closed / Lapsed

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