US4191780A
Expired / Lapsed
US
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Bromhexine derivatives and process for making same
Assignee: INODILA SpA
•
Filing: 1978-10-16
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Granted: 1980-03-04
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Expires: 1998-10-16
Abstract
Abstract Bromhexine derivatives corresponding to the following general formula <IMAGE> (I) and antitussive compositions therefrom, as well as a process for making same are described.
Inventors
- 👤 Carlo Tosi
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-09 18:16
CPC Classifications
A; A61; A61K; A61K31/00; A61K31/16; A61K31/13; A61K31/135; C; C07; C07C; C07C231/00; C07C231/02; C07C233/00; C07C233/01; C07C233/12
Claims Analysis
Total Claims: 4
Claim 1
Independent Claim
23 words
A compound selected from the group consisting of those of the formula ##STR3## wherein R is ##STR4## and the acid addition salts thereof.
Claim 2
Dependent Claim
23 words
A compound selected from the group consisting of those of the formula ##STR3## wherein R is ##STR4## and the acid addition salts thereof.
Claim 3
Dependent Claim
18 words
A compound of Formula I as defined in claim 1 which is N-(2-quaicol-glycolyl-amino-3,5-dibromobenzyl)N-cyclohexylmethylamine or the hydrochloride salt thereof.
Claim 4
Dependent Claim
26 words
Pharmaceutical composition comprising an antitussive effective amount of a compound of formula I in claim 1 or its acid addition salt in a pharmaceutically acceptable carrier.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1983-03-04 | 1983-09-03 | 1984-03-04 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1987-03-04 | 1987-09-03 | 1988-03-04 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1991-03-04 | 1991-09-03 | 1992-03-04 | $7700.00 | Window Closed / Lapsed |