US3917696A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Dihalogen-acetamino-benzylamines and process for preparing the same
Assignee: Ferrer Internacional SA
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Filing: 1974-09-20
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Granted: 1975-11-04
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Expires: 1994-09-20
Abstract
Abstract The invention relates to novel dihalogen-acetamino-benzylamines having the formula WHEREIN Hal is halogen and R is a cyclohexyl or an adamantyl group and the pharmaceutically acceptable acid addition salts thereof. Further the invention comprises the process for the manufacture of the new compounds by reacting 1-bromomethyl-3,5dihalo-N,N-diacetylaniline with N-methyl-adamantine or N-methylcyclohexylamine. The novel compounds are possessed of spasmolytic and antitussive activity.
Inventors
- 👤 Carlos Ferrer
- 👤 Juan Colome
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-09 19:02
CPC Classifications
C; C07; C07C; C07C233/00
Claims Analysis
Total Claims: 8
Claim 1
Independent Claim
13 words
A COMPOUND SELECTED FROM THE GROUP CONSISTING OF A COMPOUND OF THE FORMULA
Claim 2
Dependent Claim
13 words
A COMPOUND SELECTED FROM THE GROUP CONSISTING OF A COMPOUND OF THE FORMULA
Claim 3
Dependent Claim
12 words
A compound according to claim 1 wherein Hal is bromine or iodine.
Claim 4
Dependent Claim
17 words
A compound according to claim 1 in the form of its hydrochloric acid salt having the formula
Claim 5
Dependent Claim
9 words
A compound according to claim 1 designated N-(3,5-diiodo-2-acetaminobenzyl)-N-methylcyclohexylamine hydrochloride.
Claim 6
Dependent Claim
9 words
A compound according to claim 1 designated N-(3,5-diiodo-2-acetaminobenzyl)-N-methyladamantine hydrochloride.
Claim 7
Dependent Claim
9 words
A compound according to claim 1 designated N-(3,5-dibromo-2-acetaminobenzyl)-N-methyladamantine hydrochloride.
Claim 8
Dependent Claim
24 words
A process of making a compound according to claim 1 in the free base form comprising reacting 1-bromomEthyl-3,5-dihalo-N,N-diacetylaniline with N-methyladamantine or N-nethylcyclohexylamine under reflux.
References Cited (Backward Citations)
US3852058A
Cited
US3108038A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1978-11-03 | 1979-05-05 | 1979-11-04 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1982-11-03 | 1983-05-05 | 1983-11-04 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1986-11-03 | 1987-05-05 | 1987-11-04 | $7700.00 | Window Closed / Lapsed |