Patent US4191751A successfully refreshed from Google Patents.
US4191751A
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Method for promoting growth of new connective tissue over surface wounds
Assignee: Mentor Worldwide LLC
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Filing: 1977-12-05
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Granted: 1980-03-04
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Expires: 1997-12-05
Abstract
Abstract Method for promoting the growth of new connective tissue over a surface wound wherein at least a portion of the epithelium has been damaged or removed. The method comprises coating the wound with a composition consisting essentially of a connective tissue promoting agent selected from the group consisting of: (1) pulverized absorbable gelatin sponge, (2) aminocaproic acid, (3) a compound of the formula 4NH 2 CH 2 (CH 2 ) 4 COOH.CaX 2 wherein X is chloride or bromide, or (4) mixtures thereof, said composition being present in an amount sufficient to produce new connective tissue over the surface wound. The process is particularly useful for treating both contaminated and uncontaminated, denuded, ulcerated, and/or burned tissue.
Inventors
- 👤 Sheldon K. Gottlieb
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 20:52
CPC Classifications
A; A61; A61L; A61L15/00; A61L15/16; A61L15/42; A61L15/64; A61K; A61K31/00; A61K31/185; A61K31/19; A61K31/195; A61K31/197; A61K35/00; A61K35/12; A61K35/14; A61K35/16; A61K38/00; A61K38/16; A61K38/17; A61K38/39; A61L15/44; A61L2300/00; A61L2300/20; A61L2300/21; A61L2300/40; A61L2300/404; A61L2300/406; A61L2300/412
Claims Analysis
Total Claims: 11
Claim 1
Independent Claim
78 words
A method for promoting the growth of new connective tissue over a surface wound wherein at least a portion of the epithelium has been damaged or removed which comprises coating said wound with a composition consisting essentially of a connective tissue promoting agent of pulverized absorbable gelatin sponge, wherein plasma is present at the situs of the wound, said composition being present in an amount sufficient to promote the production of new connective tissue over said surface wound.
Claim 2
Independent Claim
78 words
A method for promoting the growth of new connective tissue over a surface wound wherein at least a portion of the epithelium has been damaged or removed which comprises coating said wound with a composition consisting essentially of a connective tissue promoting agent of pulverized absorbable gelatin sponge, wherein plasma is present at the situs of the wound, said composition being present in an amount sufficient to promote the production of new connective tissue over said surface wound.
Claim 3
Dependent Claim
16 words
The method of claim 1 which comprises coating at least a major portion of said wound.
Claim 4
Dependent Claim
29 words
The method of claim 2 wherein said composition contains from about 5 to 50 mg. of said pulverized absorbable gelatin sponge for each 0.3 to 0.5 cc of plasma.
Claim 5
Dependent Claim
27 words
The method of claim 2 wherein said composition further comprises from about 12.5 to 75 mg. of aminocaproic acid for each 0.3 to 0.5 cc. of plasma.
Claim 6
Dependent Claim
44 words
The method of claim 4 comprising from about 5 to 50 mg. of said pulverized absorbable gelatin sponge for each 0.3 to 0.5 cc. of plasma and from about 12.5 to 75 mg. of aminocaproic acid for each 0.3 to 0.5 cc. of plasma.
Claim 7
Dependent Claim
23 words
The method of claim 5 wherein said surface wound is contaminated and said composition further comprises at least one antibiotic agent incorporated therein.
Claim 8
Dependent Claim
32 words
The method of claim 6 wherein said composition is applied over said surface wound in an amount sufficient to provide a coating having a thickness of between about 1 to 5 mm.
Claim 9
Dependent Claim
17 words
The method of claim 6 wherein the thickness of said coating is between 2 to 3 mm.
Claim 10
Dependent Claim
28 words
The method of claim 6 wherein said composition further comprises between about 5 and 50 mg. of finely divided collagen for each 0.3 to 0.5 cc. of plasma.
Claim 11
Dependent Claim
51 words
The method of claim 1 wherein said composition further comprises a second connective tissue promoting agent selected from the group consisting of: (1) aminocaproic acid, (2) a compound of the formula: 4NH 2 CH 2 (CH 2 ) 4 COOH.CaX 2 wherein X is chloride or bromide, and (3) mixtures thereof.
References Cited (Backward Citations)
US3325366A
Cited
US3767784A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1983-03-04 | 1983-09-03 | 1984-03-04 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1987-03-04 | 1987-09-03 | 1988-03-04 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1991-03-04 | 1991-09-03 | 1992-03-04 | $7700.00 | Window Closed / Lapsed |