Patent US4190655A successfully refreshed from Google Patents.
US4190655A
Expired / Lapsed
US
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Amiloride citrate
Assignee: Merck and Co Inc
•
Filing: 1978-08-28
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Granted: 1980-02-26
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Expires: 1998-08-28
Abstract
Abstract A novel salt of amiloride particularly amiloride citrate has been discovered. Because of its inherent insolubility and less bitter taste, it would lend itself to be more easily formulated into oral liquids, sustained release formulations and chewable tablets than would amiloride hydrochloride.
Inventors
- 👤 Joseph DeMarco
- 👤 Gerald S. Brenner
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 18:37
CPC Classifications
C; C07; C07D; C07D241/00; C07D241/02; C07D241/10; C07D241/14; C07D241/24; C07D241/26; C07C; C07C59/00; C07C59/235; C07C59/245; C07C59/265
Claims Analysis
Total Claims: 7
Claim 1
Independent Claim
6 words
A compound of the formula: ##STR2##
Claim 2
Dependent Claim
6 words
A compound of the formula: ##STR2##
Claim 3
Dependent Claim
25 words
A pharmaceutical composition useful in the treatment of edema and hypertension which comprises a pharmaceutically acceptable amount of amiloride citrate and a pharmaceutically acceptable carrier.
Claim 4
Dependent Claim
25 words
A pharmaceutical composition useful in the treatment of edema and hypertension which comprises a pharmaceutically acceptable amount of amiloride citrate and a pharmaceutically acceptable carrier.
Claim 5
Independent Claim
25 words
A method of treating edema and hypertension which comprises administering to a patient in need of such treatment a pharmaceutically acceptable amount of amiloride citrate.
Claim 6
Independent Claim
25 words
A method of treating edema and hypertension which comprises administering to a patient in need of such treatment a pharmaceutically acceptable amount of amiloride citrate.
Claim 7
Dependent Claim
24 words
A method of treatment according to claim 3 wherein the amount of amiloride citrate administered is between 5 mg and 30 mg per day.
References Cited (Backward Citations)
US3313813A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1983-02-25 | 1983-08-27 | 1984-02-26 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1987-02-25 | 1987-08-27 | 1988-02-26 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1991-02-25 | 1991-08-27 | 1992-02-26 | $7700.00 | Window Closed / Lapsed |