Hydrophilic polymers and contact lenses of high water content

Claim 2

A contact lens adapted for extended wear hydrated to a water content of about 60% to 95% and having an oxygen permeability of at least about ##EQU3## a tensile strength of at least about 2 kg/cm 2 , and an elongation at break of at least 40% consisting essentially of the polymerization reaction product of at least one hydrophilic monomer, at least one hydrophobic monomer and at least one cross-linking monomer, the major hydrophilic monomer being an N-vinyl heterocyclic monomer selected from N-vinyl pyrrolidone, N-vinyl succinimide, N-vinyl-ε-caprolactam, N-vinyl pyridine, N-vinyl glutarimide, or mixtures thereof, the major hydrophobic monomer being selected from styrene, ring-substituted styrenes, or mixtures thereof, and the cross-linking monomer being selected from monomers containing two or more polymerizable double bonds per monomer unit.

Claim 3

The contact lens of claim 1 wherein the N-vinyl heterocyclic monomer is N-vinyl-2 pyrrolidone.

Claim 4

The contact lens of claim 1 wherein the interpolymer includes an auxiliary hydrophilic monomer selected from the C 1 -C 4 hydroxyalkyl esters of acrylic or methacrylic acid and olefinic acids which can be copolymerized by free radical polymerization with the other monomers in the interpolymer.

Claim 5

The contact lens of claim 1 wherein the N-vinyl heterocyclic monomer is used in a concentration of from about 80% to 95% by weight, the hydrophobic monomer in a concentration of about 5% to 25%, and cross-linking monomer in a concentration of from about 0.01% to 5%, the percents by weight being based on the total weight of monomers exclusive of cross-linking monomer.

Claim 6

The contact lens of claim 1 wherein the N-vinyl heterocyclic monomer is N-vinyl-2-pyrrolidone in a concentration of about 75% to 95% by weight, the hydrophobic monomer is styrene in a concentration of about 5% to 25%, and the cross-linker is diallyl itaconate in a concentration of about 0.01% to 5% by weight, the percents by weight being based on the total weight of monomers exclusive of cross-linking monomer.

Claim 7

A contact lens adapted for extended wear, hydrated to a water content of about 65% to 95% water and having an oxygen permeability of at least about ##EQU4## a tensile strength of from about 2 to 8 kg/cm 2 , and an elongation at break of from about 40% to 400%, consisting essentially of an interpolymer shaped to fit the eye, said interpolymer consisting essentially of the bulk polymerization reaction product of 75% to 95% of an N-vinyl heterocyclic monomer selected from N-vinyl pyrrolidone, N-vinyl succinimide, N-vinyl-ε-caprolactam, N-vinyl pyridine, N-vinyl glutarimide, or mixtures thereof, 5% to 25% of a hydrophobic monomer selected from styrene, ring-substituted styrenes, or mixtures thereof, and 0.01% to 5% of a cross-linking monomer having more than one polymerizable double bond, the percentage being percent by weight based on the total weight of the monomers exclusive of the cross-linking monomer.

Claim 8

A contact lens adapted for extended wear, hydrated to a water content of about 65% to 95% water and having an oxygen permeability of at least about ##EQU4## a tensile strength of from about 2 to 8 kg/cm 2 , and an elongation at break of from about 40% to 400%, consisting essentially of an interpolymer shaped to fit the eye, said interpolymer consisting essentially of the bulk polymerization reaction product of 75% to 95% of an N-vinyl heterocyclic monomer selected from N-vinyl pyrrolidone, N-vinyl succinimide, N-vinyl-ε-caprolactam, N-vinyl pyridine, N-vinyl glutarimide, or mixtures thereof, 5% to 25% of a hydrophobic monomer selected from styrene, ring-substituted styrenes, or mixtures thereof, and 0.01% to 5% of a cross-linking monomer having more than one polymerizable double bond, the percentage being percent by weight based on the total weight of the monomers exclusive of the cross-linking monomer.

Claim 9

The contact lens of claim 6 wherein the N-vinyl heterocyclic monomer is N-vinyl-2 pyrrolidone, the hydrophobic monomer is styrene, and the cross-linking monomer is diallyl itaconate.

Claim 10

The contact lens of claim 6 wherein the N-vinyl heterocyclic monomer is N-vinyl-2 pyrrolidone, the hydrophobic monomer is styrene, and the cross-linking monomer is allyl methacrylate.

Claim 11

A contact lens adapted for extended wear, hydratable to a water content of about 60% to 95% water and when so hydrated having an oxygen permeability of at least about ##EQU5## a tensile strength of at least about 2 kg/cm 2 , and an elongation at break of at least 40%, consisting essentially of the polymerization reaction product of at least one hydrophilic monomer, at least one hydrophobic monomer and at least one cross-linking monomer, the major hydrophilic monomer being an N-vinyl heterocyclic monomer selected from N-vinyl pyrrolidone, N-vinyl succinimide, N-vinyl-ε-caprolactam, N-vinyl pyridine, N-vinyl glutarimide, or mixtures thereof, the major hydrophobic monomer being selected from styrene, ring-substituted styrenes, or mixtures thereof, and the cross-linking monomer being selected from monomers containing two or more polymerizable double bonds per monomer unit.

Claim 12

A contact lens adapted for extended wear, hydratable to a water content of about 60% to 95% water and when so hydrated having an oxygen permeability of at least about ##EQU5## a tensile strength of at least about 2 kg/cm 2 , and an elongation at break of at least 40%, consisting essentially of the polymerization reaction product of at least one hydrophilic monomer, at least one hydrophobic monomer and at least one cross-linking monomer, the major hydrophilic monomer being an N-vinyl heterocyclic monomer selected from N-vinyl pyrrolidone, N-vinyl succinimide, N-vinyl-ε-caprolactam, N-vinyl pyridine, N-vinyl glutarimide, or mixtures thereof, the major hydrophobic monomer being selected from styrene, ring-substituted styrenes, or mixtures thereof, and the cross-linking monomer being selected from monomers containing two or more polymerizable double bonds per monomer unit.

Claim 13

The contact lens of claim 9 wherein the N-vinyl heterocyclic monomer is N-vinyl-2 pyrrolidone.

Claim 14

The contact lens of claim 9 wherein the interpolymer includes an auxiliary hydrophilic monomer selected from the C 1 -C 4 hydroxyalkyl esters of acrylic or methacrylic acid and olefinic acids which can be copolymerized by free radical polymerization with other monomers in the interpolymer.

Claim 15

The contact lens of claim 9 wherein the N-vinyl heterocyclic monomer is used in a concentration of from about 80% to 95% by weight, the hydrophobic monomer in a concentration of about 5% to 25%, and cross-linking monomer in a concentration of from about 0.01% to 5%, the percents by weight being based on the total weight of monomers exclusive of cross-linking monomer.

Claim 16

The contact lens of claim 9 wherein the N-vinyl heterocyclic monomer is N-vinyl-2-pyrrolidone in a concentration of about 75% to 95% by weight, the hydrophobic monomer is styrene in a concentration of about 5% to 25%, and the cross-linker is diallyl itaconate in a concentration of about 0.01% to 5% by weight, the percents by weight being based on the total weight of monomers exclusive of cross-linking monomer.