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US4180771A Expired / Lapsed US ⏱️ 0.0 years remaining

Chemical-sensitive field-effect transistor

Assignee: Airco Inc
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Filing: 1977-12-02
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Granted: 1979-12-25
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Expires: 1997-12-02
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Abstract

Abstract The invention relates to an insulated-gate field effect transistor which is adapted for detecting and measuring various chemical properties such as ion activity in a solution. The device has a chemically sensitive layer which overlies a portion of a substrate other than that covered by the gate insulator. When this chemically sensitive layer is exposed to a solution or other substance, the electric field in the substrate is modified which changes the conductance of the channel between a source region and a drain region. The change in conductance is related to the chemical exposure and can be detected with a current meter.

Inventors

  • 👤 Henry Guckel

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-23 21:33
CPC Classifications
A; A61; A61B; A61B5/00; A61B5/145; A61B5/14542; A61B5/1468; A61B5/1473; G; G01; G01N; G01N27/00; G01N27/26; G01N27/403; G01N27/414

Claims Analysis

Total Claims: 11
Claim 1
Independent Claim 190 words
A field-effect transistor device for measuring a chemical property of a substance to which the device is exposed, comprising: a semiconductor substrate; a source region in contact with the substrate and located near a first surface of the substrate; a drain region in contact with the substrate, located near the first surface of the substrate and spaced apart from the source region; a gate insulator which overlies a first area of the first surface of the substrate between the source and drain regions; three electrodes for providing a separate electrical connection to the source region, drain region, and gate insulator; and a layer of chemically sensitive material which overlies a second area of the substrate separate from the first area and which has an active surface for exposure to the substance, said chemically sensitive material connected in series with the substrate and located on the opposite side of the substrate from the gate insulator, said second area located sufficiently near the source and drain regions so that exposure of the chemically sensitive material to the substance results in a change of the electrical conductance between the source and drain regions.
Claim 2
Dependent Claim 190 words
A field-effect transistor device for measuring a chemical property of a substance to which the device is exposed, comprising: a semiconductor substrate; a source region in contact with the substrate and located near a first surface of the substrate; a drain region in contact with the substrate, located near the first surface of the substrate and spaced apart from the source region; a gate insulator which overlies a first area of the first surface of the substrate between the source and drain regions; three electrodes for providing a separate electrical connection to the source region, drain region, and gate insulator; and a layer of chemically sensitive material which overlies a second area of the substrate separate from the first area and which has an active surface for exposure to the substance, said chemically sensitive material connected in series with the substrate and located on the opposite side of the substrate from the gate insulator, said second area located sufficiently near the source and drain regions so that exposure of the chemically sensitive material to the substance results in a change of the electrical conductance between the source and drain regions.
Claim 3
Dependent Claim 20 words
The device of claim 1 in which the chemically sensitive material lies on the substrate directly opposite the gate insulator.
Claim 4
Dependent Claim 32 words
The device of claim 2 further comprising an encapsulating layer of a material which is impervious to the test substance and which has an opening to allow exposure of the active surface.
Claim 5
Dependent Claim 47 words
The device of claim 2 further comprising: a reference electrode attached to the device on the same side of the substrate as the chemically sensitive material and having a surface for exposure to the substance; and a contact for making an electrical connection to the reference electrode.
Claim 6
Dependent Claim 29 words
The device of claim 2 wherein the chemically sensitive material is a membrane which interacts with a particular kind of ion when exposed to a solution containing such ions.
Claim 7
Dependent Claim 13 words
The device of claim 5 wherein the membrane is a pH sensitive glass.
Claim 8
Dependent Claim 15 words
The device of claim 5 wherein the membrane is a polymeric material containing an ion-exchanger.
Claim 9
Dependent Claim 14 words
The device of claim 1 comprising a probe for insertion into the human body.
Claim 10
Dependent Claim 60 words
The device of claim 4 comprising an instrument for measuring a medically significant chemical property in a human body, and further comprising: an electric circuit which includes a potential source and a current meter connected in series with the source electrode and the drain electrode, and an electrical connection between the contact of the reference electrode and the gate electrode.
Claim 11
Dependent Claim 37 words
The device of claim 1 wherein the three electrodes are all on the same side of the substrate and the chemically sensitive material is on the opposite side of the substrate from that of the three electrodes.

References Cited (Backward Citations)

US3311756A Cited
US3381432A Cited
US3999122A Cited
US4020830A Cited
US4020830B1 Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1982-12-24 1983-06-25 1983-12-25 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1986-12-24 1987-06-25 1987-12-25 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1990-12-24 1991-06-25 1991-12-25 $7700.00 Window Closed / Lapsed

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