Patent US4175073A successfully refreshed from Google Patents.
US4175073A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Reactive derivatives of HS-group-containing polymers
Assignee: Cytiva Sweden AB
•
Filing: 1978-03-02
•
Granted: 1979-11-20
•
Expires: 1998-03-02
Abstract
Abstract A novel class of reactive derivatives of polymers containing HS-groups is disclosed in which derivatives a number of the HS-groups are converted to a disulphide group of the formula -S-S-A-Z, where A is a hydrocarbon residue having 1-10 carbon atoms and Z is a group ##STR1## or acid addition salts of the last mentioned group, where n is 2 or 3, R 1 is 2-pyridyl, 5-nitro-2-pyridyl or 4-pyridyl and R 2 is methyl or ethyl. The novel derivatives may be used, for example, as thiolating agents or as carriers for e.g. enzymes or other proteins etc.
Inventors
- 👤 Jan P. E. Carlsson
- 👤 Rolf E. A. V. Axen
- 👤 Hakan N. Y. Drevin
- 👤 Goran E. S. Lindgren
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 17:35
CPC Classifications
C; C08; C08B; C08B37/00; C08B37/0006; C08B37/0036; C08B37/0039; Y; Y10; Y10S; Y10S530/00; Y10S530/81; Y10S530/812; Y10S530/815
Claims Analysis
Total Claims: 9
Claim 1
Independent Claim
67 words
A reactive derivative of an HS-group-containing polymer, wherein a number of HS-groups are converted to a disulphide group of the formula --S--S--A--Z where A is a hydrocarbon residue having 1-10 carbon atoms and Z is a group ##STR14## or acid addition salts of the last mentioned group, where n is 2 or 3, R 1 is 2-pyridyl, 5-nitro-2-pyridyl or 4-pyridyl and R 2 is methyl or ethyl.
Claim 2
Dependent Claim
67 words
A reactive derivative of an HS-group-containing polymer, wherein a number of HS-groups are converted to a disulphide group of the formula --S--S--A--Z where A is a hydrocarbon residue having 1-10 carbon atoms and Z is a group ##STR14## or acid addition salts of the last mentioned group, where n is 2 or 3, R 1 is 2-pyridyl, 5-nitro-2-pyridyl or 4-pyridyl and R 2 is methyl or ethyl.
Claim 3
Dependent Claim
14 words
A reactive derivative according to claim 1 wherein the polymer is a water-insoluble polymer.
Claim 4
Dependent Claim
17 words
A reactive derivative according to claim 1 wherein A is a hydrocarbon residue having 1-6 carbon atoms.
Claim 5
Dependent Claim
21 words
A reactive derivative according to claim 1 wherein Z is the group ##STR15## and A is --CH 2 --CH 2 --.
Claim 6
Dependent Claim
14 words
A reactive derivative according to claim 4 wherein the polymer is a polysaccharide derivative.
Claim 7
Dependent Claim
14 words
A reactive derivative according to claim 4 wherein the polymer is an agarose derivative.
Claim 8
Dependent Claim
12 words
A reactive derivative according to claim 4 wherein the polymer is cross-linked.
Claim 9
Dependent Claim
19 words
A reactive derivative according to claim 7 wherein the cross-linked polymer is insoluble in water but swellable in water.
References Cited (Backward Citations)
US3666739A
Cited
US3947352A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1982-11-19 | 1983-05-21 | 1983-11-20 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1986-11-19 | 1987-05-21 | 1987-11-20 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1990-11-19 | 1991-05-21 | 1991-11-20 | $7700.00 | Window Closed / Lapsed |