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US4174402A
Expired / Lapsed
US
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Method for the prophylaxis of SRS-A-induced symptoms
Assignee: STWB Inc
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Filing: 1978-08-17
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Granted: 1979-11-13
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Expires: 1998-08-17
Abstract
Abstract A method for inhibiting the symptoms induced by SRS-A released in a mammal susceptible to said SRS-A which comprises administering to said mammal an amount effective for inhibiting said symptoms of a compound selected from the group consisting of 9-benzoyl-12,3,4,-tetrahydrocarbazole-3-carboxylic acid, 9-benzoyl-6-methoxy-1,2,3,4-tetrahydrocarbazole-3-carboxylic acid, 9-benzoyl-1,2,3,4-tetrahydrocarbazole-4-carboxylic acid, 9-(4-toluoyl)-1,2,3,4-tetrahydrocarbazole-4-carboxylic acid, 9-benzoyl-6-methoxy-1,2,3,4-tetrahydrocarbazole-4-carboxylic acid and 9-benzoyl-6-methyl-1,2,3,4-tetrahydrocarbazole-4-carboxylic acid; or a pharmaceutically acceptable salt of said compound.
Inventors
- 👤 Zigurd E. Mielens
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-01 09:55
CPC Classifications
A; A61; A61K; A61K31/00; A61K31/33; A61K31/395; A61K31/40
Claims Analysis
Total Claims: 14
Claim 1
Independent Claim
67 words
A method for inhibiting the symptoms induced by SRS-A in a mammal having an allergic condition in which SRS-A is a causative factor which comprises prophylactically administering to said mammal an amount effective for inhibiting said symptoms of a compound selected from the group consisting of 9-benzoyl-1,2,3,4-tetrahydrocarbazole-3-carboxylic acid, 9-benzoyl-6-methoxy-1,2,3,4-tetrahydrocarbazole-3-carboxylic acid, 9-benzoyl-1,2,3,4-tetrahydrocarbazole-4-carboxylic acid, 9-(4-toluoyl)-1,2,3,4-tetrahydrocarbazole-4carboxylic acid, 9-benzoyl-6-methoxy-1,2,3,4-tetrahydrocarbazole-4-carboxylic acid and 9-benzoyl-6-methyl-1,2,3,4-tetrahydrocarbazole-4-carboxylic acid; or a pharmaceutically acceptable salt of said compound.
Claim 2
Independent Claim
67 words
A method for inhibiting the symptoms induced by SRS-A in a mammal having an allergic condition in which SRS-A is a causative factor which comprises prophylactically administering to said mammal an amount effective for inhibiting said symptoms of a compound selected from the group consisting of 9-benzoyl-1,2,3,4-tetrahydrocarbazole-3-carboxylic acid, 9-benzoyl-6-methoxy-1,2,3,4-tetrahydrocarbazole-3-carboxylic acid, 9-benzoyl-1,2,3,4-tetrahydrocarbazole-4-carboxylic acid, 9-(4-toluoyl)-1,2,3,4-tetrahydrocarbazole-4carboxylic acid, 9-benzoyl-6-methoxy-1,2,3,4-tetrahydrocarbazole-4-carboxylic acid and 9-benzoyl-6-methyl-1,2,3,4-tetrahydrocarbazole-4-carboxylic acid; or a pharmaceutically acceptable salt of said compound.
Claim 3
Dependent Claim
12 words
The method according to claim 1 wherein the compound is administered orally.
Claim 4
Dependent Claim
19 words
The method according to claim 1 wherein the compound administered is 9-benzoyl-6-methoxy-1,2,3,4-tetrahydrocarbazole-3-carboxylic acid or a pharmaceutically acceptable salt thereof.
Claim 5
Dependent Claim
12 words
The method according to claim 3 wherein the compound is administered orally.
Claim 6
Dependent Claim
13 words
The method according to claim 3 wherein the compound administered is 9-benzoyl-6-methoxy-1,2,3,4-tetrahydrocarbazole-3-carboxylic acid.
Claim 7
Dependent Claim
12 words
The method according to claim 5 wherein the compound is administered orally.
Claim 8
Independent Claim
63 words
A method for inhibiting the symptoms of allergic bronchial asthma induced by SRS-A in a mammal having said asthma which comprises prophylactically administering to said mammal an amount effective for inhibiting said symptoms of a compound selected from the group consisting of 9-benzoyl-1,2,3,4-tetrahydrocarbazole-3-carboxylic acid, 9-benzoyl-6-methoxy-1,2,3,4-tetrahydrocarbazole-3-carboxylic acid, 9-benzoyl-1,2,3,4-tetrahydrocarbazole-4-carboxylic acid, 9-(4-toluoyl)-1,2,3,4-tetrahydrocarbazole-4-carboxylic acid, 9-benzoyl-6-methoxy-1,2,3,4-tetrahydrocarbazole-4-carboxylic acid and 9-benzoyl-6-methyl-1,2,3,4-tetrahydrocarbazole-4-carboxylic acid; or a pharmaceutically acceptable salt of said compound.
Claim 9
Independent Claim
63 words
A method for inhibiting the symptoms of allergic bronchial asthma induced by SRS-A in a mammal having said asthma which comprises prophylactically administering to said mammal an amount effective for inhibiting said symptoms of a compound selected from the group consisting of 9-benzoyl-1,2,3,4-tetrahydrocarbazole-3-carboxylic acid, 9-benzoyl-6-methoxy-1,2,3,4-tetrahydrocarbazole-3-carboxylic acid, 9-benzoyl-1,2,3,4-tetrahydrocarbazole-4-carboxylic acid, 9-(4-toluoyl)-1,2,3,4-tetrahydrocarbazole-4-carboxylic acid, 9-benzoyl-6-methoxy-1,2,3,4-tetrahydrocarbazole-4-carboxylic acid and 9-benzoyl-6-methyl-1,2,3,4-tetrahydrocarbazole-4-carboxylic acid; or a pharmaceutically acceptable salt of said compound.
Claim 10
Dependent Claim
12 words
The method according to claim 7 wherein the compound is administered orally.
Claim 11
Dependent Claim
19 words
The method according to claim 7 wherein the compound administered is 9-benzoyl-6-methoxy-1,2,3,4-tetrahydrocarbazole-3-carboxylic acid or a pharmaceutically acceptable salt thereof.
Claim 12
Dependent Claim
12 words
The method according to claim 9 wherein the compound is administered orally.
Claim 13
Dependent Claim
13 words
The method according to claim 9 wherein the compound administered is 9-benzoyl-6-methoxy-1,2,3,4-tetrahydrocarbazole-3-carboxylic acid.
Claim 14
Dependent Claim
12 words
The method according to claim 11 wherein the compound is administered orally.
References Cited (Backward Citations)
US3948939A
Cited
US3882148A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1982-11-12 | 1983-05-14 | 1983-11-13 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1986-11-12 | 1987-05-14 | 1987-11-13 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1990-11-12 | 1991-05-14 | 1991-11-13 | $7700.00 | Window Closed / Lapsed |