Patent US4173704A successfully refreshed from Google Patents.
US4173704A
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Dithio aminoacid derivatives
Assignee: ER Squibb and Sons LLC
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Filing: 1978-05-26
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Granted: 1979-11-06
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Expires: 1998-05-26
Abstract
Abstract A method for alleviating or reducing angiotensin related hypertension in hypertensive mammals comprises administering to such hypertensive mammals an effective amount of an angiotensin converting enzyme inhibitor selected from a group of mercaptoacyl aminoacids.
Inventors
- 👤 Miquel A. Ondetti
- 👤 David W. Cushman
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-09 00:57
CPC Classifications
C; C07; C07D; C07D233/00; C07D233/54; C07D233/64; C07D209/00; C07D209/02; C07D209/04; C07D209/10; C07D209/18; C07D209/20
Claims Analysis
Total Claims: 9
Claim 1
Independent Claim
44 words
A compound of the formula ##STR12## or physiologically acceptable salt thereof, wherein n is 0, 1 or 2; R 1 is imidazol-4-yl-lower alkylene; R 2 , R 3 and R 4 each is hydrogen, lower alkyl or phenyl-lower alkylene; and R 5 is ##STR13##
Claim 2
Dependent Claim
44 words
A compound of the formula ##STR12## or physiologically acceptable salt thereof, wherein n is 0, 1 or 2; R 1 is imidazol-4-yl-lower alkylene; R 2 , R 3 and R 4 each is hydrogen, lower alkyl or phenyl-lower alkylene; and R 5 is ##STR13##
Claim 3
Dependent Claim
21 words
A compound as in claim 1 wherein R 2 is hydrogen; and R 3 is hydrogen, lower alkyl or phenyl-lower alkylene.
Claim 4
Dependent Claim
11 words
A compound as in claim 1 wherein R 3 is hydrogen.
Claim 5
Dependent Claim
11 words
A compound as in claim 1 wherein R 4 is hydrogen.
Claim 6
Dependent Claim
10 words
A compound as in claim 1 wherein n is 0.
Claim 7
Dependent Claim
10 words
A compound as in claim 1 wherein n is 1.
Claim 8
Dependent Claim
12 words
A compound as in claim 1 wherein R 4 is lower alkyl.
Claim 9
Dependent Claim
11 words
A compound as in claim 1 wherein R 1 is imidazolyl-4-methyl.
References Cited (Backward Citations)
US3991077A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1982-11-05 | 1983-05-07 | 1983-11-06 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1986-11-05 | 1987-05-07 | 1987-11-06 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1990-11-05 | 1991-05-07 | 1991-11-06 | $7700.00 | Window Closed / Lapsed |