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Therapeutic preparations for peptic ulcers comprising aliphatic ketone derivative

Assignee: Eisai Co Ltd
•
Filing: 1978-05-23
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Granted: 1979-09-25
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Expires: 1998-05-23
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Abstract

Abstract A therapeutic preparation having excellent effect for peptic ulcers with low toxicity which comprises aliphatic ketone derivative of the general formula: ##STR1## wherein represents a saturated or unsaturated bond, R 1 is hydrogen or a lower alkyl group, R 2 is hydrogen atom, a lower alkyl group or a lower alkylcarbonyl group, R 3 is an aliphatic hydrocarbon group of the general formula: ##STR2## WHEREIN L, M AND N ARE 0 OR 1, PROVIDED THAT L+M+N≧2; AND A, B, C, D, E AND F ARE HYDROGEN ATOM, OR THEY MAY FORM A BOND OF A--B, C--D OR E--F, PROVIDED THAT IF THE BOND IS A SATURATED BOND, THE A, B, C, D, E AND F REPRESENT ALL HYDROGEN ATOM.

Inventors

  • 👤 Shizumasa Kijima
  • 👤 Isao Yamatsu
  • 👤 Yuichi Inai
  • 👤 Toshiharu Ohgoh
  • 👤 Manabu Murakami

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-11-08 07:43
CPC Classifications
A; A61; A61K; A61K31/00; A61K31/12; A43; A43D; A43D25/00; A43D25/18; A61P; A61P1/00; A61P1/04; B; B05; B05C; B05C11/00; B05C11/10; B05C11/1042; B05C5/00; B05C5/001; C; C07; C07C; C07C45/00; C07C45/61; C07C45/62; C07C45/67; C07C45/673; C07C45/676; C08; C08L; C08L77/00; C08L77/06; C08L77/08; C09; C09D; C09D5/00; C09D5/002; C09J; C09J123/00; C09J123/02; C09J163/00; C09J177/00; C09J177/06; C09J177/08; C09J5/00; C09J5/06; C09J9/00; C09J9/005; C08L2666/00; C08L2666/02; C08L2666/14; C08L2666/22

Claims Analysis

Total Claims: 3
Claim 1
Independent Claim 124 words
A method of treating a peptic ulcer which comprises administering to a patient an effective ulcer treating amount of an aliphatic ketone derivative of the general formula: ##STR9## wherein represents a saturated or unsaturated bond, R 1 is hydrogen or a lower alkyl group, R 2 is a hydrogen atom, a lower alkyl group, or a lower alkylcarbonyl group, R 3 is an aliphatic hydrocarbon group of the formula: ##STR10## wherein l, m and n are 0 or 1, provided that l+m+n√2; and a, b, c, d, e and f are hydrogen atoms, or they may form a bond of a-b, c-d, e-f, provided that if the bond is a saturated bond, the a, b, c, d, e and f all represent hydrogen atoms.
Claim 2
Independent Claim 124 words
A method of treating a peptic ulcer which comprises administering to a patient an effective ulcer treating amount of an aliphatic ketone derivative of the general formula: ##STR9## wherein represents a saturated or unsaturated bond, R 1 is hydrogen or a lower alkyl group, R 2 is a hydrogen atom, a lower alkyl group, or a lower alkylcarbonyl group, R 3 is an aliphatic hydrocarbon group of the formula: ##STR10## wherein l, m and n are 0 or 1, provided that l+m+n√2; and a, b, c, d, e and f are hydrogen atoms, or they may form a bond of a-b, c-d, e-f, provided that if the bond is a saturated bond, the a, b, c, d, e and f all represent hydrogen atoms.
Claim 3
Dependent Claim 24 words
A method according to claim 1, wherein the aliphatic ketone derivative is administered to the patient in a dosage of 50-2000 mg a day.

References Cited (Backward Citations)

US3801652A Cited
US3824319A Cited
US3729486A Cited
US3978230A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1982-09-24 1983-03-26 1983-09-25 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1986-09-24 1987-03-26 1987-09-25 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1990-09-24 1991-03-26 1991-09-25 $7700.00 Window Closed / Lapsed

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