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Method of treating depression with thiourea derivatives

Assignee: Hoffmann La Roche Inc
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Filing: 1978-09-25
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Granted: 1979-09-25
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Expires: 1998-09-25
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Abstract

Abstract A method of utilizing thiourea derivatives of the formulas <IMAGE> I and <IMAGE> II wherein R, R1, R2, R3 and X are as hereinafter described, as agents in the treatment of depression, is described.

Inventors

  • 👤 Michael R. Cohen
  • 👤 Richard W. Kierstead
  • 👤 Jefferson W. Tilley

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-11-07 11:16
CPC Classifications
C; C07; C07D; C07D295/00; C07D295/04; C07D295/12; C07D295/125; C07D295/13; C07C; C07C279/00; C07C279/18; C07C335/00; C07C335/04; C07C335/16; C07C335/30; C07C335/32

Claims Analysis

Total Claims: 3
Claim 1
Independent Claim 61 words
A method of treating depression which comprises administering to a host requiring such treatment an effective amount of a thiourea derivative of the formula ##STR15## wherein R is lower alkyl; R 1 and R 2 , independently, are halogen; R 3 is amino or piperidino; and X is sulfur or imino, or an addition salt thereof with a pharmaceutically acceptable acid.
Claim 2
Independent Claim 61 words
A method of treating depression which comprises administering to a host requiring such treatment an effective amount of a thiourea derivative of the formula ##STR15## wherein R is lower alkyl; R 1 and R 2 , independently, are halogen; R 3 is amino or piperidino; and X is sulfur or imino, or an addition salt thereof with a pharmaceutically acceptable acid.
Claim 3
Dependent Claim 13 words
A method in accordance with claim 1, wherein the thiourea derivative is 1-(2-aminoethyl)-3-(2,6-dichlorophenyl)-thiourea.

References Cited (Backward Citations)

No citation records indexed.

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1982-09-24 1983-03-26 1983-09-25 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1986-09-24 1987-03-26 1987-09-25 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1990-09-24 1991-03-26 1991-09-25 $7700.00 Window Closed / Lapsed

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