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US4163849A
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US
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Piperazinylpyrazines
Assignee: Merck and Co Inc
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Filing: 1978-03-17
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Granted: 1979-08-07
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Expires: 1998-03-17
Abstract
Abstract Substituted piperazinylpyrazines and pharmaceutically acceptable salts thereof which have pharmacological activity as anorexigenic agents.
Inventors
- 👤 William C. Lumma, Jr.
- 👤 Walfred S. Saari
- 👤 Anthony G. Zacchei
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-09 18:57
CPC Classifications
C; C07; C07D; C07D241/00; C07D241/02; C07D241/10; C07D241/14; C07D241/20
Claims Analysis
Total Claims: 7
Claim 1
Independent Claim
34 words
A compound of the formula: ##STR4## wherein R 1 is allyl, cyclopropyl, cyclopropylalkyl of 4-6 carbon atoms or propaniminooxycarbonyl and R 2 is alkyl of 1-4 carbon atoms and the pharmaceutically acceptable salts thereof.
Claim 2
Dependent Claim
34 words
A compound of the formula: ##STR4## wherein R 1 is allyl, cyclopropyl, cyclopropylalkyl of 4-6 carbon atoms or propaniminooxycarbonyl and R 2 is alkyl of 1-4 carbon atoms and the pharmaceutically acceptable salts thereof.
Claim 3
Dependent Claim
11 words
A compound as in claim 1 wherein the compound is 6-chloro-2-(4-allyl-1-piperazinyl)-pyrazine.
Claim 4
Dependent Claim
11 words
A compound as in claim 1 wherein the compound is 6-chloro-2-(4-cyclopropyl-1-piperazinyl)-pyrazine.
Claim 5
Dependent Claim
11 words
A compound as in claim 1 wherein the compound is 6-chloro-2-(4-cyclopropylmethyl-1-piperazinyl)-pyrazine.
Claim 6
Dependent Claim
11 words
A compound as in claim 1 wherein the compound is 6-chloro-2-[4-(2'-propaniminooxycarbonyl)-1-piperazinyl]-pyrazine.
Claim 7
Dependent Claim
11 words
A compound as in claim 1 wherein the compound is 6-chloro-2-(4-methyl-3-oxo-1-piperazinyl)-pyrazine.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1982-08-06 | 1983-02-05 | 1983-08-07 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1986-08-06 | 1987-02-05 | 1987-08-07 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1990-08-06 | 1991-02-05 | 1991-08-07 | $7700.00 | Window Closed / Lapsed |