Controlled antacid delivery form and method of treatment therewith

Claim 1

A noncariogenic controlled antacid delivery composition compressed into lozenges having a hardness of at least 15 kg/in 2 , including a mixture of a magnesium antacid salt and an aluminum antacid salt, said salts having different rates of reaction with hydrochloric acid, in a matrix including in combination mannitol, a gel-forming swelling agent selected from the group consisting of sodium carboxymethyl cellulose and xanthum gum, and a hydrophobic magnesium, calcium or aluminum salt of a fatty acid selected from the group consisting of stearic, palmitic, oleic and lauric acids, the mannitol being present in an amount from about 25 to 60 percent by weight, the gel forming agent being present in an amount from about 3 to 10 percent by weight, and the hydrophobic magnesium, calcium or aluminum salt of a fatty acid being present in an amount from about 1 to 5 percent by weight, to provide a lozenge which dissolves in about 15 to 60 minutes in a user's mouth, each of said lozenges containing an effective amount of antacid salts to maintain the pH of the user's gastric juice above 3.5.