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US4163451A Expired / Lapsed US ⏱️ 0.0 years remaining

Interactive method and digitally timed apparatus for cardiac pacing arrhythmia treatment

Assignee: Pacesetter Inc
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Filing: 1977-10-26
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Granted: 1979-08-07
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Expires: 1997-10-26
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Abstract

Abstract The cardiac pacer disclosed herein responds to a premature heartbeat by first digitally measuring the time interval between a pair of successive sensed heartbeats and establishing an escape interval for stimulation which is shorter than the measured heartbeat interval. Pacing at this shorter escape interval enables the pacer to capture and control the heartbeat rate. By repeatedly incrementing the digital value representing the escape value on successive stimulated heartbeats, the heart is then caused to slow down until a preselected desired rate is established. Preferably, the sensing and timing between heartbeats continues during the slowdown process so that, if, at any time, a natural heartbeat occurs earlier than the stimulation pulse at the then extant escape interval, the escape interval is reset to a shorter time so that capture will be re-established.

Inventors

  • 👤 Alan F. Lesnick
  • 👤 Peter P. Tarjan

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-23 18:58
CPC Classifications
A; A61; A61N; A61N1/00; A61N1/18; A61N1/32; A61N1/36; A61N1/362; A61N1/3621

Claims Analysis

Total Claims: 21
Claim 1
Independent Claim 121 words
Cardiac pacing apparatus comprising: timing means for generating a series of clock pulses; means responsive to heartbeats; means for counting clock pulses occurring from a first heartbeat to a second heartbeat thereby to obtain a first value representing the time interval between heartbeats; means for generating a value which is smaller than said first value and which represents an escape interval; means for counting clock pulses occurring after said second sensed heartbeat to obtain a running time value; means for comparing said running time value with said escape interval value; and means responsive to said comparison for generating a stimulating pulse and for incrementing said escape interval value if said running time value becomes substantially equal to said escape interval value.
Claim 2
Dependent Claim 121 words
Cardiac pacing apparatus comprising: timing means for generating a series of clock pulses; means responsive to heartbeats; means for counting clock pulses occurring from a first heartbeat to a second heartbeat thereby to obtain a first value representing the time interval between heartbeats; means for generating a value which is smaller than said first value and which represents an escape interval; means for counting clock pulses occurring after said second sensed heartbeat to obtain a running time value; means for comparing said running time value with said escape interval value; and means responsive to said comparison for generating a stimulating pulse and for incrementing said escape interval value if said running time value becomes substantially equal to said escape interval value.
Claim 3
Dependent Claim 150 words
Cardiac pacing apparatus comprising: means for generating a series of clock pulses; means for counting, after a heartbeat, to obtain a time value based on said clock pulses; means for sensing heartbeats; means for preselecting an AUTO rate value representing a maximum interval between heartbeats; pulse output means, said pulse output means being operative to generate a stimulation pulse when said time value reaches a level corresponding to said AUTO rate value; means responsive to a sensed, naturally occurring heartbeat for generating an escape interval value which corresponds to a period shorter than the interval from the preceding heartbeat, said pulse output means being thereafter operative to generate a stimulation pulse when said time value reaches a level corresponding to said escape interval value; and means for incrementing said escape interval value each time a stimulation pulse is generated at the time corresponding to the then extant escape interval value.
Claim 4
Dependent Claim 150 words
Cardiac pacing apparatus comprising: means for generating a series of clock pulses; means for counting, after a heartbeat, to obtain a time value based on said clock pulses; means for sensing heartbeats; means for preselecting an AUTO rate value representing a maximum interval between heartbeats; pulse output means, said pulse output means being operative to generate a stimulation pulse when said time value reaches a level corresponding to said AUTO rate value; means responsive to a sensed, naturally occurring heartbeat for generating an escape interval value which corresponds to a period shorter than the interval from the preceding heartbeat, said pulse output means being thereafter operative to generate a stimulation pulse when said time value reaches a level corresponding to said escape interval value; and means for incrementing said escape interval value each time a stimulation pulse is generated at the time corresponding to the then extant escape interval value.
Claim 5
Dependent Claim 159 words
Cardiac pacing apparatus comprising: means for generating a series of clock pulses; means for counting, after a heartbeat, to obtain a time value based on said clock pulses; register means for holding a value representing an escape interval; pulse output means, said pulse output means being operative to generate a stimulation pulse when said time value reaches said escape interval value; means for sensing heartbeats; means for preselecting an AUTO rate value representing a maximum interval between heartbeats and, in the absence of sensed naturally occurring heartbeats, entering said AUTO rate value in said register; means responsive to a sensed, naturally occurring heartbeat for generating an escape interval value which corresponds to a period shorter than the interval from the preceding heartbeat, and for entering said shorter value in said register; and means for incrementing said escape interval value in said register each time a stimulation pulse is generated until said escape interval value reaches said AUTO rate value.
Claim 6
Dependent Claim 159 words
Cardiac pacing apparatus comprising: means for generating a series of clock pulses; means for counting, after a heartbeat, to obtain a time value based on said clock pulses; register means for holding a value representing an escape interval; pulse output means, said pulse output means being operative to generate a stimulation pulse when said time value reaches said escape interval value; means for sensing heartbeats; means for preselecting an AUTO rate value representing a maximum interval between heartbeats and, in the absence of sensed naturally occurring heartbeats, entering said AUTO rate value in said register; means responsive to a sensed, naturally occurring heartbeat for generating an escape interval value which corresponds to a period shorter than the interval from the preceding heartbeat, and for entering said shorter value in said register; and means for incrementing said escape interval value in said register each time a stimulation pulse is generated until said escape interval value reaches said AUTO rate value.
Claim 7
Dependent Claim 16 words
Apparatus as set forth in claim 3 including means for preselecting the magnitude of the increments.
Claim 8
Dependent Claim 34 words
Apparatus as set forth in claim 3 including means for selecting the amount by which the initial escape interval is shorter than the interval between the sensed, naturally occurring heartbeat and the preceding heartbeat.
Claim 9
Dependent Claim 17 words
Apparatus as set forth in claim 3 wherein said means for counting comprises a discrete digital counter.
Claim 10
Dependent Claim 16 words
Apparatus as set forth in claim 6 wherein said pulse output means includes a discrete comparator.
Claim 11
Dependent Claim 42 words
Apparatus as set forth in claim 7 wherein said means for generating an escape interval value includes a second discrete digital counter and wherein said entering means includes means for transferring a value from said second counter to the first said counter.
Claim 12
Dependent Claim 24 words
Apparatus as set forth in claim 3 wherein said pulse output means includes means for comparing said time value with said escape interval value.
Claim 13
Dependent Claim 26 words
Apparatus as set forth in claim 9 wherein said means for counting and said means for comparing comprise storage registers and the accumulator of a microprocessor.
Claim 14
Dependent Claim 17 words
Apparatus as set forth in claim 10 wherein said sensing means generates an interrupt to said microprocessor.
Claim 15
Dependent Claim 26 words
Apparatus as set forth in claim 11 wherein the sequence of operations of said microprocessor is controlled by a program stored in a read only memory.
Claim 16
Independent Claim 91 words
The method of electrically pacing a heart which comprises: sensing heartbeats; digitally timing the interval between successive heartbeats; generating an escape interval value which corresponds to a period shorter than the timed interval between a first heartbeat and a second, naturally occurring heartbeat; following a naturally occurring heartbeat, generating a stimulating pulse when the timed interval corresponds to the escape interval value and then incrementing the escape interval value, the incrementing continuing on successive stimulation cycles until said escape interval value reaches a preselected value corresponding to a minimum heartbeat rate.
Claim 17
Independent Claim 91 words
The method of electrically pacing a heart which comprises: sensing heartbeats; digitally timing the interval between successive heartbeats; generating an escape interval value which corresponds to a period shorter than the timed interval between a first heartbeat and a second, naturally occurring heartbeat; following a naturally occurring heartbeat, generating a stimulating pulse when the timed interval corresponds to the escape interval value and then incrementing the escape interval value, the incrementing continuing on successive stimulation cycles until said escape interval value reaches a preselected value corresponding to a minimum heartbeat rate.
Claim 18
Independent Claim 150 words
The method of electrically pacing a heart which comprises: generating stimulating pulses at preselected intervals to effect pacing at a preselected fixed rate, the intervals being determined by digitally counting down a clock signal by a preselectable factor; sensing for naturally occurring heartbeats occurring during a period preceding the completion of each such preselected interval and, if a naturally occurring heartbeat is detected during said period, generating an escape interval value which corresponds to a period shorter than that between the sensed heartbeat and the preceding stimulated heartbeat; following a detected, naturally occurring heartbeat, generating stimulating pulses at intervals corresponding to the then extant escape interval value by digitally counting down from said clock signal and, upon the generation of each pulse, incrementing the escape interval value, the incrementing continuing until the escape interval becomes essentially equal to said preselected interval at which point the pacing reverts to fixed rate.
Claim 19
Independent Claim 150 words
The method of electrically pacing a heart which comprises: generating stimulating pulses at preselected intervals to effect pacing at a preselected fixed rate, the intervals being determined by digitally counting down a clock signal by a preselectable factor; sensing for naturally occurring heartbeats occurring during a period preceding the completion of each such preselected interval and, if a naturally occurring heartbeat is detected during said period, generating an escape interval value which corresponds to a period shorter than that between the sensed heartbeat and the preceding stimulated heartbeat; following a detected, naturally occurring heartbeat, generating stimulating pulses at intervals corresponding to the then extant escape interval value by digitally counting down from said clock signal and, upon the generation of each pulse, incrementing the escape interval value, the incrementing continuing until the escape interval becomes essentially equal to said preselected interval at which point the pacing reverts to fixed rate.
Claim 20
Dependent Claim 158 words
Cardiac pacing apparatus for treating cardiac arrhythmias, said apparatus comprising: pacer input means for electrically detecting heartbeats; pacer output means for generating electrical signals at levels appropriate for cardiac stimulation; means for coupling said input means and said output means to a patient's heart; a digital data processor whose sequence of operation is controllable by means of a stored program, said processor including means for testing input parameters and means for generating output signals, said pacer output means being connected to said processor output signal generating processor to provide a changed input parameter thereto when a heartbeat is detected; a read only memory having a program permanently stored therein, said program defining the sequential reaction of the processor output signal of input parameters coupled to said processor as a result of detected naturally occurring heartbeat sequences, said program including instruction sequences for measuring the intervals between successive heartbeats and revising stimulation sequences in response to the values obtained.
Claim 21
Dependent Claim 158 words
Cardiac pacing apparatus for treating cardiac arrhythmias, said apparatus comprising: pacer input means for electrically detecting heartbeats; pacer output means for generating electrical signals at levels appropriate for cardiac stimulation; means for coupling said input means and said output means to a patient's heart; a digital data processor whose sequence of operation is controllable by means of a stored program, said processor including means for testing input parameters and means for generating output signals, said pacer output means being connected to said processor output signal generating processor to provide a changed input parameter thereto when a heartbeat is detected; a read only memory having a program permanently stored therein, said program defining the sequential reaction of the processor output signal of input parameters coupled to said processor as a result of detected naturally occurring heartbeat sequences, said program including instruction sequences for measuring the intervals between successive heartbeats and revising stimulation sequences in response to the values obtained.

References Cited (Backward Citations)

US3942534A Cited
US3921642A Cited
US4005282A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1982-08-06 1983-02-05 1983-08-07 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1986-08-06 1987-02-05 1987-08-07 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1990-08-06 1991-02-05 1991-08-07 $7700.00 Window Closed / Lapsed

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