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Patent US4158630A successfully refreshed from Google Patents.
US4158630A
Expired / Lapsed
US
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Chromatographic multi-sample valving apparatus
Assignee: Individual
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Filing: 1978-02-24
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Granted: 1979-06-19
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Expires: 1998-02-24
Abstract
Abstract Apparatus for delivering different samples to a liquid chromatograph is disclosed. The valving apparatus includes a commutated valve having N loops, where N is a whole number integer. The loops are isolated from one another. Selected loops are cycled by rotation of an inlet and outlet connected to selected loops. The valving apparatus further includes a valve mechanism having multiple ports which connect with an inlet, a sample holding loop, a liquid chromatographic pump, a chromatographic column for separation of constituents of the sample and other functional connections to carry on chromatographic analysis.
Inventors
- 👤 Stanley D. Stearns
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-09 03:40
CPC Classifications
G; G01; G01N; G01N30/00; G01N30/02; G01N30/04; G01N30/16; G01N30/20; G01N30/84; G01N2030/8411
Claims Analysis
Total Claims: 8
Claim 1
Independent Claim
150 words
Sample injection apparatus for delivering a sequence of samples to a chromatographic detection apparatus which injection apparatus comprises: (a) loop selector valve means having a plurality of sample storage loops connected thereto and which further includes inlet and outlet means whereby individual samples can be stored in individual isolated storage loops connected thereto; and (b) chromatographic column valve means including an inlet port and flow path for introduction of a specimen of interest to be stored in a particular storage loop of said loop selector valve means, a second flow path selectively serially communicated with said selected storage loop and a chromatographic column, and a third flow path selectively opened and closed through said column valve means from a sampler pump to said loop selector valve means and selectively flowing to said column valve means through said selected sample holding loop to deliver a selected sample to a chromatographic column.
Claim 2
Dependent Claim
150 words
Sample injection apparatus for delivering a sequence of samples to a chromatographic detection apparatus which injection apparatus comprises: (a) loop selector valve means having a plurality of sample storage loops connected thereto and which further includes inlet and outlet means whereby individual samples can be stored in individual isolated storage loops connected thereto; and (b) chromatographic column valve means including an inlet port and flow path for introduction of a specimen of interest to be stored in a particular storage loop of said loop selector valve means, a second flow path selectively serially communicated with said selected storage loop and a chromatographic column, and a third flow path selectively opened and closed through said column valve means from a sampler pump to said loop selector valve means and selectively flowing to said column valve means through said selected sample holding loop to deliver a selected sample to a chromatographic column.
Claim 3
Dependent Claim
57 words
The apparatus of claim 1 wherein said loop selector valve means comprises N sample loops, and each of said sample loops is connected to two ports, and wherein the ports are grouped for connection into an inlet manifold and a separate outlet manifold and further including rotor means for commutating one of the loops to said manifolds.
Claim 4
Dependent Claim
130 words
The apparatus of claim 1 wherein said last named valve means incorporates at least nine ports, and wherein the ports provided therein include: (a) a sample injection port; (b) a second port serving as an outlet port connecting said valve means with said loop selector valve means; (c) third and fourth ports connected with a holding loop; (d) fifth and sixth port means adapted to be connected with the chromatograph pump and adapted to be connected to the chromatographic column; (e) a seventh port adapted to be connected as an inlet port with said loop selector valve means; (f) an eighth port adapted to be a sampler pump port adapted to be connected with a sampler pump; and (g) a ninth port adapted to be connected as a vent port.
Claim 5
Dependent Claim
41 words
The apparatus of claim 3 wherein said ports comprise ten in number and are switchable between a pair of valve positions, said valve means comprising a rotor switchable to achieve two valve positions and two combinations of connections by said ports.
Claim 6
Dependent Claim
22 words
The apparatus of claim 4 including a rotatable rotor in a stator operable between two positions to achieve switching as described above.
Claim 7
Dependent Claim
22 words
The apparatus of claim 1 including a single sample holding loop connected to a pair of ports on said column valve means.
Claim 8
Dependent Claim
19 words
The apparatus of claim 1 wherein said column valve means is a two position, ten port, single valve apparatus.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1982-06-18 | 1982-12-18 | 1983-06-19 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1986-06-18 | 1986-12-18 | 1987-06-19 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1990-06-18 | 1990-12-18 | 1991-06-19 | $7700.00 | Window Closed / Lapsed |