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US4156778A
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Substituted bis-benzimidazolyl compounds; preparation and use thereof
Assignee: Hoechst AG
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Filing: 1978-03-14
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Granted: 1979-05-29
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Expires: 1998-03-14
Abstract
Abstract Substituted bis-benzimidazolyl compounds of the formula ##STR1## are disclosed, wherein A is thiophenediyl, furanediyl, phenylene, or phenoxyphenylene, and R 1 is ##STR2## where R 2 -R 10 are independently hydrogen, alkyl, aminoalkyl, N-alkylaminoalkyl, N,N-dialkylaminoalkyl, or phenyl, or any two of R 2 -R 10 taken together are C 2 -C 4 alkylene, as are methods of making the compounds, which are useful as chemotherapeutic agents in the treatment of protozoal and viral diseases.
Inventors
- 👤 Manfred Rosner
- 👤 Heinz Loewe
- 👤 Wolfgang Raether
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-29 21:58
CPC Classifications
C; C07; C07D; C07D239/00; C07D239/02; C07D239/06; A; A61; A61P; A61P31/00; A61P31/12; A61P33/00; A61P33/02; C07D233/00; C07D233/04; C07D233/20; C07D233/24; C07D235/00; C07D235/02; C07D235/04; C07D235/18; C07D239/70; C07D307/00; C07D307/02; C07D307/34; C07D307/56; C07D307/68; C07D333/00; C07D333/02; C07D333/04; C07D333/26; C07D333/38
Claims Analysis
Total Claims: 2
Claim 1
Independent Claim
91 words
A substituted bis-benzimidazolyl compound of the formula ##STR14## or a physiologically acceptable salt thereof, wherein A is 2,5-thiophenediyl, 2,5-furanediyl, p-phenylene, m-phenylene or 4,4'-phenoxyphenylene, and wherein R 1 is ##STR15## wherein in turn the radicals R 2 to R 10 , independently of one another, are hydrogen, alkyl having 1-4 carbon atoms, aminoalkyl, N-aminoalkyl, or N,N-dialkylaminoalkyl wherein each alkyl has from 1 to 4 carbon atoms each, or phenyl, or wherein two of the radicals R 2 to R 10 together are an alkylene bridge having 2, 3 or 4 carbon atoms.
Claim 2
Dependent Claim
91 words
A substituted bis-benzimidazolyl compound of the formula ##STR14## or a physiologically acceptable salt thereof, wherein A is 2,5-thiophenediyl, 2,5-furanediyl, p-phenylene, m-phenylene or 4,4'-phenoxyphenylene, and wherein R 1 is ##STR15## wherein in turn the radicals R 2 to R 10 , independently of one another, are hydrogen, alkyl having 1-4 carbon atoms, aminoalkyl, N-aminoalkyl, or N,N-dialkylaminoalkyl wherein each alkyl has from 1 to 4 carbon atoms each, or phenyl, or wherein two of the radicals R 2 to R 10 together are an alkylene bridge having 2, 3 or 4 carbon atoms.
References Cited (Backward Citations)
US2733244A
Cited
US3103518A
Cited
US2995564A
Cited
US3337578A
Cited
US3287469A
Cited
US3179669A
Cited
US3971782A
Cited
US3992403A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1982-05-28 | 1982-11-27 | 1983-05-29 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1986-05-28 | 1986-11-27 | 1987-05-29 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1990-05-28 | 1990-11-27 | 1991-05-29 | $7700.00 | Window Closed / Lapsed |