Patent US4154934A successfully refreshed from Google Patents.
US4154934A
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Mercaptoacylamino derivatives of heterocyclic carboxylic acids
Assignee: ER Squibb and Sons LLC
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Filing: 1978-08-11
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Granted: 1979-05-15
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Expires: 1998-08-11
Abstract
Abstract New mercaptoacyl derivatives of heterocyclic carboxylic acids which have the general formula ##STR1## are useful as angiotensin converting enzyme inhibitors.
Inventors
- 👤 Jack Bernstein
- 👤 Kathryn A. Losee
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-26 05:48
CPC Classifications
C; C07; C07D; C07D207/00; C07D207/46; C07D207/50
Claims Analysis
Total Claims: 18
Claim 1
Independent Claim
64 words
A compound of the formula ##STR9## wherein R is hydrogen or lower alkyl; R 1 and R 4 each is hydrogen, lower alkyl or phenyl-lower alkyl; R 2 is hydrogen, R 5 --CO-- or ##STR10## R 3 is hydrogen or hydroxy; R 5 is lower alkyl, phenyl or phenyl-lower alkyl; m is 1, 2 or 3; n is 0 or 1; and salts thereof.
Claim 2
Dependent Claim
64 words
A compound of the formula ##STR9## wherein R is hydrogen or lower alkyl; R 1 and R 4 each is hydrogen, lower alkyl or phenyl-lower alkyl; R 2 is hydrogen, R 5 --CO-- or ##STR10## R 3 is hydrogen or hydroxy; R 5 is lower alkyl, phenyl or phenyl-lower alkyl; m is 1, 2 or 3; n is 0 or 1; and salts thereof.
Claim 3
Dependent Claim
10 words
A compound as in claim 1 wherein m is 2.
Claim 4
Dependent Claim
10 words
A compound as in claim 1 wherein m is 1.
Claim 5
Dependent Claim
10 words
A compound as in claim 1 wherein m is 3.
Claim 6
Dependent Claim
11 words
A compound as in claim 1 wherein R 3 is hydrogen.
Claim 7
Dependent Claim
11 words
A compound as in claim 1 wherein R 3 is hydroxy.
Claim 8
Dependent Claim
11 words
A compound as in claim 1 wherein R 2 is hydrogen.
Claim 9
Dependent Claim
10 words
A compound as in claim 1 wherein n is 0.
Claim 10
Dependent Claim
11 words
A compound as in claim 1 wherein R 2 is ##STR11##
Claim 11
Dependent Claim
53 words
A compound as in claim 1 wherein R and R 1 each is hydrogen or lower alkyl; R 2 is hydrogen or R 5 --CO; R 3 is hydrogen or hydroxy; R 4 is hydrogen; R 5 is lower alkyl or phenyl; m is 2 or 3; and n is 0 or 1.
Claim 12
Dependent Claim
16 words
A compound as in claim 2 wherein R, R 2 and R 3 each is hydrogen.
Claim 13
Dependent Claim
20 words
A compound as in claim 2 wherein R and R 3 each is hydrogen and R 2 is lower alkanoyl.
Claim 14
Dependent Claim
26 words
A compound as in claim 2 wherein R, R 1 , R 2 , R 3 and R 4 each is hydrogen and n is 1.
Claim 15
Dependent Claim
27 words
A compound as in claim 2 wherein R, R 1 , R 3 and R 4 each is hydrogen, R 2 is acetyl and n is 1.
Claim 16
Dependent Claim
23 words
A compound as in claim 2 wherein R, R 2 , R 3 and R 4 each is hydrogen and n is 1.
Claim 17
Dependent Claim
24 words
A compound as in claim 2 wherein R, R 3 and R 4 each is hydrogen; R 2 is acetyl and n is 1.
Claim 18
Dependent Claim
23 words
A compound as in claim 2 wherein R, R 1 , R 2 and R 3 each is hydrogen and n is 0.
References Cited (Backward Citations)
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Cited
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Cited
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Cited
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Cited
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1982-05-14 | 1982-11-13 | 1983-05-15 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1986-05-14 | 1986-11-13 | 1987-05-15 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1990-05-14 | 1990-11-13 | 1991-05-15 | $7700.00 | Window Closed / Lapsed |