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Process for the preparation of glucoproteins as well as the use thereof

Assignee: Individual
•
Filing: 1977-01-18
•
Granted: 1979-05-08
•
Expires: 1997-01-18
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Abstract

Abstract The use of a stabilized glucoprotein for the preparation of medicaments with a potentiating action of active substances is described wherein the separate glucoprotein is stabilized with an inorganic electrolyte and/or a saccharide and albumin mixture combinations with antibiotics, ampicillin, etc., are described.

Inventors

  • 👤 Hans-Hugo Nagel

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-23 17:13
CPC Classifications
C; C12; C12P; C12P21/00; C12P21/005; A; A61; A61K; A61K38/00; A61K38/16; A61K38/17; C07; C07K; C07K14/00; C07K14/435; C07K14/46; C07K14/47; C07K14/78

Claims Analysis

Total Claims: 8
Claim 1
Independent Claim 87 words
Use of stabilised glucoprotein for the preparation of medicaments with a potentiating action on the active substances, whereby 10 2 to 10 6 parts by weight of the active medicament substance is used per 1 part by weight of glucoprotein, wherein said stabilized glucoprotein is prepared by reacting an aqueous suspension of yeast with monosaccharides and native albumin as starting substance, and separating the glucoprotein from the resulting reaction medium, and thereafter adding an inorganic electrolyte and/or a saccharide and albumin mixture thereto to stabilize the same.
Claim 2
Dependent Claim 87 words
Use of stabilised glucoprotein for the preparation of medicaments with a potentiating action on the active substances, whereby 10 2 to 10 6 parts by weight of the active medicament substance is used per 1 part by weight of glucoprotein, wherein said stabilized glucoprotein is prepared by reacting an aqueous suspension of yeast with monosaccharides and native albumin as starting substance, and separating the glucoprotein from the resulting reaction medium, and thereafter adding an inorganic electrolyte and/or a saccharide and albumin mixture thereto to stabilize the same.
Claim 3
Dependent Claim 19 words
Use according to claim 1, characterised in that the glucoprotein has an average molecular weight of 55,000 to 65,000.
Claim 4
Dependent Claim 14 words
Use according to claim 1, wherein lactose or glucose is used as the monosaccharide.
Claim 5
Dependent Claim 14 words
Use according to claim 1, wherein lactalbumin or gelatin is used as the albumin.
Claim 6
Dependent Claim 13 words
Use according to claim 1, wherein said reacting is performed at ambient temperature.
Claim 7
Dependent Claim 18 words
Use according to claim 1, wherein said reacting is performed at pH values of approximately 6 to 7.5.
Claim 8
Dependent Claim 14 words
Use according to claim 1, wherein said glucoprotein is separated by dialysis and dried.

References Cited (Backward Citations)

US3637640A Cited
US3847890A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1982-05-07 1982-11-06 1983-05-08 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1986-05-07 1986-11-06 1987-05-08 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1990-05-07 1990-11-06 1991-05-08 $7700.00 Window Closed / Lapsed

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