US4152333A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Synthetic cephalotaxine esters having antileukemic activity
Assignee: United States Department of Agriculture
•
Filing: 1978-02-22
•
Granted: 1979-05-01
•
Expires: 1998-02-22
Abstract
Abstract Six acyl esters of cephalotaxine have been synthesized by ordinary and standard procedures, and all have demonstrated chemotherapeutic activity against leukemia in animals.
Inventors
- 👤 Kenneth L. Mikolajczak
- 👤 Cecil R. Smith, Jr.
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-09 08:13
CPC Classifications
C; C07; C07D; C07D491/00; C07D491/12; C07D491/20
Claims Analysis
Total Claims: 8
Claim 1
Independent Claim
19 words
Chemotherapeutically active alkaloid compounds having the following structure: ##STR19## where R is selected from the group consisting of: ##STR20##
Claim 2
Dependent Claim
19 words
Chemotherapeutically active alkaloid compounds having the following structure: ##STR19## where R is selected from the group consisting of: ##STR20##
Claim 3
Dependent Claim
12 words
The alkaloid compound as described in claim 1 wherein R is ##STR21##
Claim 4
Dependent Claim
12 words
The alkaloid compound as described in claim 1 wherein R is ##STR22##
Claim 5
Dependent Claim
12 words
The alkaloid compound as described in claim 1 wherein R is ##STR23##
Claim 6
Dependent Claim
12 words
The alkaloid compound as described in claim 1 wherein R is ##STR24##
Claim 7
Dependent Claim
12 words
The alkaloid compound as described in claim 1 wherein R is ##STR25##
Claim 8
Dependent Claim
12 words
The alkaloid compound as described in claim 1 wherein R is ##STR26##
References Cited (Backward Citations)
US3870727A
Cited
US3959312A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1982-04-30 | 1982-10-30 | 1983-05-01 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1986-04-30 | 1986-10-30 | 1987-05-01 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1990-04-30 | 1990-10-30 | 1991-05-01 | $7700.00 | Window Closed / Lapsed |