Patent US4147692A successfully refreshed from Google Patents.
US4147692A
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Novel dipeptide derivatives, and method of measuring enzymatic activity
Assignee: Ajinomoto Co Inc
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Filing: 1978-02-17
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Granted: 1979-04-03
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Expires: 1998-02-17
Abstract
Abstract The compound 7-glycylprolylamino-4-methylcoumarin and certain of its derivatives are utilized for the diagnosis of pathological conditions such as hepatic diseases and gastric cancer by measuring the enzymatic activity of X-prolyl dipeptidyl-aminopeptidase.
Inventors
- 👤 Toshiharu Nagatsu
- 👤 Shumpei Sakakibara
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-30 09:54
CPC Classifications
C; C07; C07K; C07K5/00; C07K5/04; C07K5/06; C07K5/06008; C07K5/06017; C07K5/06026; C12; C12Q; C12Q1/00; C12Q1/34; C12Q1/37; C12Q2337/00; C12Q2337/20; C12Q2337/22; G; G01; G01N; G01N2333/00; G01N2333/90; G01N2333/914; G01N2333/948; Y; Y10; Y10S; Y10S530/00; Y10S530/802
Claims Analysis
Total Claims: 9
Claim 1
Independent Claim
8 words
7-Glycyl-prolylamino-4-methylcoumarin, and acid salts and N-endo-protected derivatives thereof.
Claim 2
Dependent Claim
8 words
7-Glycyl-prolylamino-4-methylcoumarin, and acid salts and N-endo-protected derivatives thereof.
Claim 3
Dependent Claim
16 words
The compounds of claim 1, wherein the stereochemical configuration of the proline residue is the L-form.
Claim 4
Dependent Claim
1 words
7-Glycyl-L-prolylamino-4-methylcoumarin.
Claim 5
Dependent Claim
1 words
7-Glycyl-L-prolylamino-4-methylcoumarin.
Claim 6
Dependent Claim
2 words
7-Glycyl-L-prolylamino-4-methylcoumarin p-toluenesulfonate.
Claim 7
Dependent Claim
2 words
7-Glycyl-L-prolylamino-4-methylcoumarin p-toluenesulfonate.
Claim 8
Dependent Claim
5 words
7-glycyl-prolylamino-4-methylcoumarin or acid salts thereof.
Claim 9
Dependent Claim
5 words
7-glycyl-prolylamino-4-methylcoumarin or acid salts thereof.
References Cited (Backward Citations)
US3886136A
Cited
US4018884A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1982-04-02 | 1982-10-02 | 1983-04-03 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1986-04-02 | 1986-10-02 | 1987-04-03 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1990-04-02 | 1990-10-02 | 1991-04-03 | $7700.00 | Window Closed / Lapsed |