US4145542A
Expired / Lapsed
US
⏱️ 0.0 years remaining
5- 1-Hydroxy-2-(heterocyclic-amino)!alkyl-8-hydroxy-3,4-dihydrocarbostyril derivatives
Assignee: Otsuka Pharmaceutical Co Ltd
•
Filing: 1976-11-29
•
Granted: 1979-03-20
•
Expires: 1996-11-29
Abstract
Abstract 5- 1-Hydroxy-2-(heterocyclic-amino)!alkyl-8-hydroxy-3,4-dihydrocarbostyril derivatives having the formula (I) ##STR1## wherein R 1 represents an alkyl group having 1 to 4 carbon atoms and A, when taken together with the nitrogen atom to which it is attached, form a 5- or 6-membered substituted or unsubstituted heterocyclic ring containing 1 or 2 nitrogen, or oxygen atoms as hetero atoms, the pharmaceutically acceptable acid addition salts thereof, and a process for preparing the same.
Inventors
- 👤 Kazuyuki Nakagawa
- 👤 Shiro Yoshizaki
- 👤 Shigeharu Tamada
- 👤 Kaoru Tanimura
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-30 15:51
CPC Classifications
C; C07; C07D; C07D215/00; C07D215/02; C07D215/16; C07D215/20; C07D215/24; C07D215/26
Claims Analysis
Total Claims: 4
Claim 1
Independent Claim
64 words
A 5- 1-hydroxy-2-(heterocyclic-amino)!alkyl-8-hydroxy-3,4dihydrocarbostyril derivative having the formula ##STR21## wherein R 1 represents an alkyl group having 1 to 4 carbon atoms, and A, when taken together with the nitrogen atom to which it is attached, forma a morpholino or piperazino ring which is unsubstituted or substituted by an alkyl group of 1 to 4 carbon atoms, and the pharmaceutically acceptable acid addition salts thereof.
Claim 2
Dependent Claim
64 words
A 5- 1-hydroxy-2-(heterocyclic-amino)!alkyl-8-hydroxy-3,4dihydrocarbostyril derivative having the formula ##STR21## wherein R 1 represents an alkyl group having 1 to 4 carbon atoms, and A, when taken together with the nitrogen atom to which it is attached, forma a morpholino or piperazino ring which is unsubstituted or substituted by an alkyl group of 1 to 4 carbon atoms, and the pharmaceutically acceptable acid addition salts thereof.
Claim 3
Dependent Claim
5 words
5-(1-Hydroxy-2-morpholino)propyl-8-hydroxy-3,4-dihydrocarbostyril according to claim 1.
Claim 4
Dependent Claim
5 words
5-(1-Hydroxy-2-morpholino)butyl-8-hydroxy-3,4-dihydrocarbostyril according to claim 1.
References Cited (Backward Citations)
US3994901A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1982-03-19 | 1982-09-18 | 1983-03-20 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1986-03-19 | 1986-09-18 | 1987-03-20 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1990-03-19 | 1990-09-18 | 1991-03-20 | $7700.00 | Window Closed / Lapsed |