Patent US4143054A successfully refreshed from Google Patents.
US4143054A
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7-oxabicycloheptane- and 7-oxabicycloheptene compounds
Assignee: ER Squibb and Sons LLC
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Filing: 1977-11-04
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Granted: 1979-03-06
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Expires: 1997-11-04
Abstract
Abstract New 7-oxabicycloheptane- and 7-oxabicycloheptene compounds which have the general formula ##STR1## and intermediates therefor which have the general formulas ##STR2## are useful as cardiovascular agents.
Inventors
- 👤 Peter W. Sprague
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-27 19:49
CPC Classifications
C; C07; C07D; C07D493/00; C07D493/02; C07D493/08; A; A61; A61P; A61P9/00; A61P9/08
Claims Analysis
Total Claims: 11
Claim 1
Independent Claim
57 words
A compound of the formula ##STR23## wherein R 1 is hydrogen or lower alkyl; R 2 is --CHO, --CH 2 OH or --CH═CH--R 3 -- lower alkylene-CH 3 ; R 3 is keto or hydroxymethyl; and the dotted line is an optional double bond; said lower alkyl and lower alkylene groups having up to seven carbon atoms.
Claim 2
Dependent Claim
57 words
A compound of the formula ##STR23## wherein R 1 is hydrogen or lower alkyl; R 2 is --CHO, --CH 2 OH or --CH═CH--R 3 -- lower alkylene-CH 3 ; R 3 is keto or hydroxymethyl; and the dotted line is an optional double bond; said lower alkyl and lower alkylene groups having up to seven carbon atoms.
Claim 3
Dependent Claim
32 words
A compound as in claim 1 wherein R 1 is hydrogen or lower alkyl; R 2 is --CH 2 OH or --CH═CH--R 3 -lower alkylene-CH 3 ; and R 3 is hydroxymethyl.
Claim 4
Dependent Claim
16 words
A compound as in claim 1 wherein R 2 is --CH═CH--R 3 -lower alkylene-CH 3 .
Claim 5
Dependent Claim
31 words
A compound as in claim 1 wherein R 2 is --CH═CH--R 3 -lower alkylene-CH 3 ; R 3 is hydroxymethyl and each lower alkylene group has 3 or 4 carbon atoms.
Claim 6
Dependent Claim
11 words
7-[3-(3-hydroxy-1-octenyl)-7-oxabicyclo[2.2.1]hept-2-yl]-5-heptenoic acid and C 1 -C 7 lower alkyl esters thereof.
Claim 7
Dependent Claim
11 words
7-[3-(3-hydroxy-1-octenyl)-7-oxabicyclo[2.2.1]hept-2-yl]-5-heptenoic acid and C 1 -C 7 lower alkyl esters thereof.
Claim 8
Dependent Claim
2 words
[1R-(1α,2β(5Z),3β(1E,3S*),4α)]-7-[3-(3-hydroxy-1-octenyl)-7-oxabicyclo[2.2.1]hept-2-yl]-5-heptenoic acid.
Claim 9
Dependent Claim
2 words
[1R-(1α,2β(5Z),3β(1E,3S*),4α)]-7-[3-(3-hydroxy-1-octenyl)-7-oxabicyclo[2.2.1]hept-2-yl]-5-heptenoic acid.
Claim 10
Dependent Claim
2 words
[1R-(1α,2β(5Z),3β(1E,3R*),4α)]-7-[3-(3-hydroxy-1-octenyl)-7-oxabicyclo[2.2.1]hept-2-yl]-5-heptenoic acid.
Claim 11
Dependent Claim
2 words
[1R-(1α,2β(5Z),3β(1E,3R*),4α)]-7-[3-(3-hydroxy-1-octenyl)-7-oxabicyclo[2.2.1]hept-2-yl]-5-heptenoic acid.
References Cited (Backward Citations)
No citation records indexed.
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1982-03-05 | 1982-09-04 | 1983-03-06 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1986-03-05 | 1986-09-04 | 1987-03-06 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1990-03-05 | 1990-09-04 | 1991-03-06 | $7700.00 | Window Closed / Lapsed |