Patent US4141919A successfully refreshed from Google Patents.
US4141919A
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Process for producing alkoxy ketones
Assignee: Novartis Corp
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Filing: 1977-01-17
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Granted: 1979-02-27
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Expires: 1997-01-17
Abstract
Abstract A process for producing alkoxy ketones of formula I ##STR1## wherein R 1 represents an alkyl group having 1 to 8 carbon atoms, R 2 represents hydrogen or an alkyl group having 1 to 4 carbon atoms, and n represents 1 or 2, by dehydrogenation of a corresponding alkoxyalkanol on a copper-containing catalyst which has been activated by treatment with hydrogen at 120° to 450° C., in which process the activated catalyst is firstly brought into contact at 230° to 350° C. with the vapor of the alkoxyalkanol to be dehydrogenated; hydrogen is subsequently passed over the catalyst at 250° to 450° C.; and then the dehydrogenation is performed at 150° to 450° C. on the catalyst pretreated in this manner, is disclosed.
Inventors
- 👤 Claude Gremmelmaier
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-30 14:13
CPC Classifications
C; C07; C07C; C07C45/00; C07C45/002
Claims Analysis
Total Claims: 10
Claim 1
Independent Claim
160 words
A process for the production of an alkoxy ketone of the formula I ##STR4## wherein R 1 represents an alkyl group having 1 to 8 carbon atoms, R 2 represents hydrogen or an alkyl group having 1 to 4 carbon atoms, and n represents 1 or 2, by dehydrogenation of an alkoxyalkanol of the formula II ##STR5## wherein R 1 , R 2 and n have the meaning given above, on a copper-containing catalyst, which comprises the steps of: (a) treating the catalyst with hydrogen at a temperature of 120° to 450° C. for about 15 hours: (b) contacting the hydrogenated catalyst with the vapor of the alkoxyalkanol to be dehydrogenated at a temperature of 230° to 350° C. for 0.5 to 2 hours; (c) treating the catalyst again with hydrogen at a temperature of 250° to 450° C. for 0.25 to 1 hour; and (d) dehydrogenating the alkoxyalkanol of the formula at a temperature of 150° to 450° C.
Claim 2
Dependent Claim
160 words
A process for the production of an alkoxy ketone of the formula I ##STR4## wherein R 1 represents an alkyl group having 1 to 8 carbon atoms, R 2 represents hydrogen or an alkyl group having 1 to 4 carbon atoms, and n represents 1 or 2, by dehydrogenation of an alkoxyalkanol of the formula II ##STR5## wherein R 1 , R 2 and n have the meaning given above, on a copper-containing catalyst, which comprises the steps of: (a) treating the catalyst with hydrogen at a temperature of 120° to 450° C. for about 15 hours: (b) contacting the hydrogenated catalyst with the vapor of the alkoxyalkanol to be dehydrogenated at a temperature of 230° to 350° C. for 0.5 to 2 hours; (c) treating the catalyst again with hydrogen at a temperature of 250° to 450° C. for 0.25 to 1 hour; and (d) dehydrogenating the alkoxyalkanol of the formula at a temperature of 150° to 450° C.
Claim 3
Dependent Claim
131 words
A process for the activation of dehydrogenation catalysts containing copper oxide for use in the dehydrogenation of alkoxyalkanols of the formula ##STR6## wherein R 1 represents an alkyl group having 1 to 8 carbon atoms, R 2 represents hydrogen or an alkyl group having 1 to 4 carbon atoms, and n represents 1 or 2, to the corresponding carbonyl compounds, which comprises the steps of (a) treating the catalyst with hydrogen at a temperature of 120° to 450° C. for about 15 hours; (b) contacting the hydrogenated catalyst with the vapor of the alkoxyalkanol to be dehydrogenated at a temperature of 230° to 350° C. for 0.5 to 2 hours; and (c) treating the catalyst again with hydrogen at a temperature of 250° to 450° C. for 0.25 to 1 hour.
Claim 4
Dependent Claim
131 words
A process for the activation of dehydrogenation catalysts containing copper oxide for use in the dehydrogenation of alkoxyalkanols of the formula ##STR6## wherein R 1 represents an alkyl group having 1 to 8 carbon atoms, R 2 represents hydrogen or an alkyl group having 1 to 4 carbon atoms, and n represents 1 or 2, to the corresponding carbonyl compounds, which comprises the steps of (a) treating the catalyst with hydrogen at a temperature of 120° to 450° C. for about 15 hours; (b) contacting the hydrogenated catalyst with the vapor of the alkoxyalkanol to be dehydrogenated at a temperature of 230° to 350° C. for 0.5 to 2 hours; and (c) treating the catalyst again with hydrogen at a temperature of 250° to 450° C. for 0.25 to 1 hour.
Claim 5
Dependent Claim
23 words
Process according to claim 1, wherein copper oxide or mixtures of copper oxide with other metal oxides are used as the copper-containing catalyst.
Claim 6
Dependent Claim
46 words
Process according to claim 1, wherein the treatment with the vapor of the alkoxyalkanol of the formula II to be dehydrogenated is performed at 250° to 350° C., the subsequent treatment with hydrogen at 250° to 350° C. and the dehydrogenation at 200° to 400° C.
Claim 7
Dependent Claim
32 words
Process according to claim 1, wherein the dehydrogenation of the alkoxyalkanol of the formula II is performed at a temperature at most the same as that for the preceding treatment with hydrogen.
Claim 8
Dependent Claim
40 words
Process according to claim 1, wherein the dehydrogenation of an alkoxyalkanol of the formula II is performed at a temperature which is 10° to 30° C. lower than the temperature at which the preceding treatment with hydrogen has been performed.
Claim 9
Dependent Claim
25 words
Process according to claim 1, wherein 1 to 15% by weight of water is added to the alkoxyalkanol of the formula II to be dehydrogenated.
Claim 10
Dependent Claim
88 words
Process according to claim 1, wherein the starting material is an alkoxyalkanol of the formula II wherein R 1 represents an alkyl group having 1 to 4 carbon atoms, R 2 represents hydrogen or methyl, and n represents 1, in which process the dehydrogenation catalyst is firstly treated at 140° to 320° C. with hydrogen, subsequently at 250° to 300° C. with the vapour of the alkoxyalkanol to be dehydrogenated and then at 250° to 320° C. with hydrogen, and dehydrogenation is performed at 200° to 300° C.
References Cited (Backward Citations)
US1999388A
Cited
US2083877A
Cited
US2634295A
Cited
US3285714A
Cited
US3462495A
Cited
US3554930A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1982-02-26 | 1982-08-28 | 1983-02-27 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1986-02-26 | 1986-08-28 | 1987-02-27 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1990-02-26 | 1990-08-28 | 1991-02-27 | $7700.00 | Window Closed / Lapsed |