US4129560A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Process for the purification of high molecular weight peptides using non-ionic detergents
Assignee: Hoechst AG
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Filing: 1977-06-29
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Granted: 1978-12-12
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Expires: 1997-06-29
Abstract
Abstract Process for the purification of high molecular weight peptides, which have a tendency to associate, by ion exchanger chromatography in aqueous buffered solvents on acid or basic ion exchangers, which comprises dissolving non ionic detergents in the buffered solvents.
Inventors
- 👤 Manfred Zoltobrocki
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-25 10:33
CPC Classifications
C; C07; C07K; C07K1/00; C07K1/14; C07K1/16; C07K1/18; A; A23; A23K; A23K10/00; A23K10/30; A23K10/32; C07K14/00; C07K14/435; C07K14/575; C07K14/62; C07K14/625; Y; Y10; Y10S; Y10S530/00; Y10S530/827; Y10S530/854
Claims Analysis
Total Claims: 2
Claim 1
Independent Claim
73 words
A method for purifying a high molecular weight peptide selected from the group consisting of insulins, insulin analogues, insulin derivatives, natural adrenocorticotropic hormone, growth hormone, glucagon, and glycoproteid hormones of the anterior lobe of the pituitary gland, which peptides have a tendency to associate, which method comprises subjecting a buffered solution of said peptide to ion exchange chromatography on an acidic or basic ion exchanger, said buffered solution additionally comprising a non-ionic detergent.
Claim 2
Independent Claim
73 words
A method for purifying a high molecular weight peptide selected from the group consisting of insulins, insulin analogues, insulin derivatives, natural adrenocorticotropic hormone, growth hormone, glucagon, and glycoproteid hormones of the anterior lobe of the pituitary gland, which peptides have a tendency to associate, which method comprises subjecting a buffered solution of said peptide to ion exchange chromatography on an acidic or basic ion exchanger, said buffered solution additionally comprising a non-ionic detergent.
References Cited (Backward Citations)
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1981-12-11 | 1982-06-12 | 1982-12-12 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1985-12-11 | 1986-06-12 | 1986-12-12 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1989-12-11 | 1990-06-12 | 1990-12-12 | $7700.00 | Window Closed / Lapsed |