Patent US3002878A successfully refreshed from Google Patents.
Patent US4126681A successfully refreshed from Google Patents.
US4126681A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Topical composition containing acetyl salicylic acid
Assignee: Procter and Gamble Co
•
Filing: 1977-03-14
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Granted: 1978-11-21
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Expires: 1997-03-14
Abstract
Abstract Compositions especially adapted for use as vehicles for the topical administration of an anti-inflammatory amount of acetylsalicylic acid to inflamed tissue and methods for using same are provided.
Inventors
- 👤 Herbert H. Reller
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-27 10:43
CPC Classifications
A; A61; A61K; A61K9/00; A61K9/0012; A61K9/0014; A61K31/00; A61K31/60; A61K47/00; A61K47/06; A61K47/08; A61K47/10; A61K47/14; A61K8/00; A61K8/18; A61K8/30; A61K8/33; A61K8/34; A61K8/345; A61K8/37; A61K8/375; A61Q; A61Q19/00; Y; Y10; Y10S; Y10S424/00; Y10S424/13
Claims Analysis
Total Claims: 15
Claim 1
Independent Claim
78 words
An anti-inflammatory composition containing less than about 20% by weight water for topical application to inflamed tissue, comprising: (a) from about 0.1% to about 10% by weight of monoolein; (b) from about 40% to about 99% by weight of a diol having 3 or 4 carbon atoms; (c) from about 0.5% to about 10% by weight of acetylsalicylic acid; and (d) from about 0% to about 60% by weight of an alcohol having 2 or 3 carbon atoms.
Claim 2
Dependent Claim
78 words
An anti-inflammatory composition containing less than about 20% by weight water for topical application to inflamed tissue, comprising: (a) from about 0.1% to about 10% by weight of monoolein; (b) from about 40% to about 99% by weight of a diol having 3 or 4 carbon atoms; (c) from about 0.5% to about 10% by weight of acetylsalicylic acid; and (d) from about 0% to about 60% by weight of an alcohol having 2 or 3 carbon atoms.
Claim 3
Dependent Claim
18 words
A composition according to claim 1 comprising from about 30% to about 50% by weight of the alcohol.
Claim 4
Dependent Claim
58 words
A composition according to claim 1, consisting essentially of: (a) from about 0.25% to about 5% by weight of monoolein; (b) from about 40% to about 60% by weight of the diol; (c) from about 1% to about 5% by weight of acetyl salicylic acid; and (d) from about 30% to about 50% by weight of the alcohol.
Claim 5
Dependent Claim
11 words
A composition according to claim 3 wherein the diol is 1,2-propanediol.
Claim 6
Dependent Claim
11 words
A composition according to claim 4 wherein the alcohol is ethanol.
Claim 7
Independent Claim
87 words
A method for treating inflamed tissue comprising topically applying thereto a safe and effective amount of a composition containing less than about 20% by weight water comprising: (a) from about 0.1% to about 10% by weight of monoolein; (b) from about 40% to about 99% by weight of a diol having 3 or 4 carbon atoms; (c) from about 0.5% to about 10% by weight of acetylsalicylic acid; and (d) from about 0% to about 60% by weight of an alcohol having 2 or 3 carbon atoms.
Claim 8
Independent Claim
87 words
A method for treating inflamed tissue comprising topically applying thereto a safe and effective amount of a composition containing less than about 20% by weight water comprising: (a) from about 0.1% to about 10% by weight of monoolein; (b) from about 40% to about 99% by weight of a diol having 3 or 4 carbon atoms; (c) from about 0.5% to about 10% by weight of acetylsalicylic acid; and (d) from about 0% to about 60% by weight of an alcohol having 2 or 3 carbon atoms.
Claim 9
Dependent Claim
21 words
A method according to claim 6 wherein the composition contains from about 30% to about 50% by weight of the alcohol.
Claim 10
Dependent Claim
58 words
A method according to claim 6 wherein the composition comprises: (a) from about 0.25% to about 5% by weight of monoolein; (b) from about 40% to about 60% by weight of the diol; (c) from about 1% to about 5% by weight of acetylsalicylic acid; and (d) from about 30% to about 50% by weight of the alcohol.
Claim 11
Dependent Claim
11 words
A method according to claim 8 wherein the diol is 1,2-propanediol.
Claim 12
Dependent Claim
11 words
A method according to claim 9 wherein the alcohol is ethanol.
Claim 13
Dependent Claim
50 words
A method according to claim 6 wherein the inflamed tissue comprises acne or acne-like comedones and lesions, and the tissue adjacent thereto, and wherein sufficient composition to provide from about 30 micrograms to about 120 micrograms of acetylsalicylic acid per centimeter 2 of treated tissue is applied in each treatment.
Claim 14
Dependent Claim
44 words
A method according to claim 6 wherein the inflamed tissue is the product of a burn, and wherein sufficient composition to provide from about 40 micrograms to about 400 micrograms of acetylsalicylic acid per centimeter 2 of treated tissue is applied in each treatment.
Claim 15
Dependent Claim
45 words
A method according to claim 6 wherein the inflamed tissue is the product of an insect bite, and wherein sufficient composition to provide from about 40 micrograms to about 400 micrograms of acetylsalicylic acid per centimeter 2 of treated tissue is applied in each treatment.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1981-11-20 | 1982-05-22 | 1982-11-21 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1985-11-20 | 1986-05-22 | 1986-11-21 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1989-11-20 | 1990-05-22 | 1990-11-21 | $7700.00 | Window Closed / Lapsed |