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Luliberin analogs

Assignee: Imperial Chemical Industries Ltd
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Filing: 1977-05-26
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Granted: 1978-11-07
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Expires: 1997-05-26
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Abstract

Abstract The disclosure relates to novel polypeptides which are analogues of luliberin and which possess luliberin antagonist activity, to processes for their manufacture and to compositions containing them. Typical of the polypeptides disclosed is ##STR1## in which A is D-Phe, D-Trp or a direct bond.

Inventors

  • 👤 Anand S. Dutta
  • 👤 Michael B. Giles

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-26 08:46
CPC Classifications
C; C07; C07K; C07K5/00; C07K5/04; C07K5/06; C07K5/06191; C07K7/00; C07K7/04; C07K7/23; A; A61; A61K; A61K38/00; Y; Y10; Y10S; Y10S930/00; Y10S930/01; Y10S930/13

Claims Analysis

Total Claims: 4
Claim 1
Independent Claim 14 words
A polypeptide of the formula: ##STR8## and the pharmaceutically- and veterinarily-acceptable acid-addition salts thereof.
Claim 2
Dependent Claim 14 words
A polypeptide of the formula: ##STR8## and the pharmaceutically- and veterinarily-acceptable acid-addition salts thereof.
Claim 3
Dependent Claim 35 words
A pharmaceutical or veterinary composition comprising as active ingredient an effective amount of a polypeptide as claimed in claim 1 in association with a major amount of a non-toxic pharmaceutically- or veterinarily-acceptable diluent or carrier.
Claim 4
Dependent Claim 25 words
A method of controlling fertility in warm-blooded animals by inhibiting ovulation which comprises administering an effective amount of a polypeptide as claimed in claim 1.

References Cited (Backward Citations)

US3928307A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1981-11-06 1982-05-08 1982-11-07 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1985-11-06 1986-05-08 1986-11-07 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1989-11-06 1990-05-08 1990-11-07 $7700.00 Window Closed / Lapsed

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