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Derivatives of mercaptopyridine-1-oxide

Assignee: Colgate Palmolive Co
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Filing: 1977-04-27
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Granted: 1978-10-24
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Expires: 1997-04-27
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Abstract

Abstract Quaternary ammonium salts and benzyl mercaptans of amino derivatives of mercaptopyridine-1-oxide, including 1-acylamino- and 2-alkoxycarbonylamino-6-pyridine-1-oxide, having particular utility as antimicrobial agents per se and in skin cleansing detergent compositions, shampoos, hair dressings, disinfectants, preservatives and the like.

Inventors

  • 👤 Miriam Lois Douglass

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-11-03 19:38
CPC Classifications
C; C07; C07D; C07D213/00; C07D213/02; C07D213/89; A; A01; A01N; A01N43/00; A01N43/34; A01N43/40; A01N47/00; A01N47/08; A01N47/10; A01N47/18; A01N47/22; A61; A61K; A61K8/00; A61K8/18; A61K8/30; A61K8/49; A61K8/4906; A61K8/4933; A61Q; A61Q17/00; A61Q17/005; A61Q19/00; A61Q19/10; A61K2800/00; A61K2800/40; A61K2800/52; A61K2800/524; A61Q5/00; A61Q5/02; A61Q5/06; Y; Y10; Y10S; Y10S424/00; Y10S424/04

Claims Analysis

Total Claims: 5
Claim 1
Independent Claim 133 words
A mercaptopyridine-1-oxide compound having the following structural formula: ##STR10## wherein R is selected from the group consisting of the acyl radical R 0 C═O and the alkoxycarbonyl radical R 0 --OC═O, where R 0 is a C 1 -C 6 alkyl, aryl selected from the class consisting of phenyl or naphthyl or aralkyl, said alkyl portion having 1-6 carbons, or halobenzyl; R 1 , R 2 and R 3 are each independently selected from the group consisting of hydrogen, methyl, two of said terms may represent methoxy and the other hydrogen, one of said terms may represent ethyl, n-butyl, methoxy, ethoxy, phenyl, bromophenyl, chlorophenyl, trichlorophenyl, naphthyl, chlorobenzyl, dichlorobenzyl or furyl and the other two terms represent hydrogen; and R 4 is selected from the group consisting of a quaternary ammonium ion and benzyl.
Claim 2
Dependent Claim 133 words
A mercaptopyridine-1-oxide compound having the following structural formula: ##STR10## wherein R is selected from the group consisting of the acyl radical R 0 C═O and the alkoxycarbonyl radical R 0 --OC═O, where R 0 is a C 1 -C 6 alkyl, aryl selected from the class consisting of phenyl or naphthyl or aralkyl, said alkyl portion having 1-6 carbons, or halobenzyl; R 1 , R 2 and R 3 are each independently selected from the group consisting of hydrogen, methyl, two of said terms may represent methoxy and the other hydrogen, one of said terms may represent ethyl, n-butyl, methoxy, ethoxy, phenyl, bromophenyl, chlorophenyl, trichlorophenyl, naphthyl, chlorobenzyl, dichlorobenzyl or furyl and the other two terms represent hydrogen; and R 4 is selected from the group consisting of a quaternary ammonium ion and benzyl.
Claim 3
Dependent Claim 19 words
A compound in accordance with claim 1, wherein R 1 , R 2 and R 3 are all hydrogen.
Claim 4
Dependent Claim 71 words
A compound according to claim 1, wherein R 4 is the quaternary ammonium ion R 5 R 6 R 7 R 8 N + wherein R 5 and R 6 are each hydrogen or C 1 -C 3 alkyl, R 7 is hydrogen, C 1 -C 3 alkyl, benzyl or C 12 -C 22 alkyl and R 8 is hydrogen, C 1 -C 3 alkyl or C 12 -C 22 alkyl.
Claim 5
Dependent Claim 14 words
A compound according to claim 3, which is cetyl trimethyl ammonium salt of 2-acetamido-6-mercaptopyridine-1-oxide.

References Cited (Backward Citations)

US2922790A Cited
US3773770A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1981-10-23 1982-04-24 1982-10-24 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1985-10-23 1986-04-24 1986-10-24 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1989-10-23 1990-04-24 1990-10-24 $7700.00 Window Closed / Lapsed

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