Substituted 1,2,4-triazole derivatives

Abstract

Abstract New 1-alkyl-3,5-disubstituted-1,2,4-triazole derivatives of following formula I <IMAGE> I wherein R may represent phenyl; phenyl substituted by a radical selected from (C1-4)alkyl, e.g. methyl, ethyl, propyl, isopropyl, butyl, sec.-butyl, isobutyl or tert.-butyl, (C1-4)alkoxy, e.g. methoxy, ethoxy, propoxy, butoxy, isobutyloxy or tert.-butoxy, fluoro, chloro, bromo, nitro, amino, cyano, carbamoyl, carboxy, hydroxymethyl, methylenedioxy and trifluoromethyl; dichlorophenyl; dimethoxyphenyl; 3,4,5-trimethoxyphenyl; R1 may represent phenyl, phenyl substituted by a radical selected from (C1-4)alkyl as above defined, (C1-4)alkoxy as above defined; fluoro, chloro, bromo, hydroxymethyl, (C2-4)aliphatic acyloxymethyl, e.g. acetoxymethyl, propionyloxymethyl or butyryloxymethyl, carbamoyloxymethyl, bromomethyl and dimethylaminomethyl; dimethylphenyl; dimethoxyphenyl; phenyl contemporaneously substituted by o-hydroxymethyl and chloro; R2 represents a (C1-4)alkyl group as above defined; WITH THE PROVISO THAT R and R1 cannot simultaneously represent phenyl; WITH THE FURTHER PROVISO THAT, WHEN R is phenyl, R1 cannot be p-chlorophenyl; AND PROCESSES FOR THEIR PREPARATION.

Inventors

• 👤 Amedeo Omodei-Sale
• 👤 Giorgio Pifferi
• 👤 Pietro Consonni
• 👤 Alberto Diena
• 👤 Bonaccorso Rosselli del Turco

Bibliographic Details