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US4118587A
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Novel 4-phenoxy-5-sulfamylbenzoic acid derivatives
Assignee: Hoffmann La Roche Inc
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Filing: 1976-11-01
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Granted: 1978-10-03
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Expires: 1996-11-01
Abstract
Abstract Novel 3-(butylamino) or (1-pyrrolidinyl)-4-phenoxy-5-sulfamylbenzoic acid derivatives where the butyl group contains either a double bond or a hydroxy, ketone, acid or ester functional group or groups, said compounds being useful as diuretics.
Inventors
- 👤 David Llewellyn Coffen
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-09 05:54
CPC Classifications
C; C07; C07D; C07D207/00; C07D207/02; C07D207/18; C07D207/22; C07D207/24; C07D207/26; C07D207/263; C07D207/27; C07D295/00; C07D295/04; C07D295/14; C07D295/155
Claims Analysis
Total Claims: 5
Claim 1
Independent Claim
37 words
A compound of the formula ##STR30## wherein R 1 is individually hydrogen, R 2 is individually hydroxy or taken together with R 1 is oxo, R 5 is hydrogen or lower alkanoyl, or pharmaceutically acceptable salts thereof.
Claim 2
Dependent Claim
37 words
A compound of the formula ##STR30## wherein R 1 is individually hydrogen, R 2 is individually hydroxy or taken together with R 1 is oxo, R 5 is hydrogen or lower alkanoyl, or pharmaceutically acceptable salts thereof.
Claim 3
Dependent Claim
12 words
The compound of claim 1 wherein said compound is 3-(γ, δ-dihydroxybutylamino)-4-phenoxy-5-sulfamylbenzoic acid.
Claim 4
Dependent Claim
11 words
The compound of claim 1 wherein said compound is 3-(γ-hydroxybutylamino)-4-phenoxy-5-sulfamylbenzoic acid.
Claim 5
Dependent Claim
11 words
The compound of claim 1 wherein said compound is 3-(γ-oxo-δacetoxybutylamino)-4-phenoxy-5-sulfamylbenzoic acid.
References Cited (Backward Citations)
US3991097A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1981-10-02 | 1982-04-03 | 1982-10-03 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1985-10-02 | 1986-04-03 | 1986-10-03 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1989-10-02 | 1990-04-03 | 1990-10-03 | $7700.00 | Window Closed / Lapsed |