US4118316A
Expired / Lapsed
US
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Quaternized siliceous supports for gel permeation chromatography
Assignee: ECC SPECIALTY CHEMICALS Inc
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Filing: 1976-10-13
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Granted: 1978-10-03
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Expires: 1996-10-13
Abstract
Abstract Controlled porosity supports having a siliceous surface are treated with a silane compound followed by treatment with a quaternizing agent to introduce quaternary ammonium moieties on the beads which are used to perform molecular size separations on cationic polymers.
Inventors
- 👤 Charles P. Talley
- 👤 Guy M. Bradley
- 👤 Ronald T. Guliana
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-25 02:37
CPC Classifications
B; B01; B01J; B01J20/00; B01J20/281; B01J20/291; B01D; B01D15/00; B01D15/08; B01D15/26; B01D15/34; B01J20/22; B01J20/26; B01J20/262; B01J20/265; B01J20/28; B01J20/28054; B01J20/28078; B01J20/30; B01J20/3078; B01J20/3092; B01J20/32; B01J20/3202; B01J20/3204; B01J20/3231; B01J20/3242; B01J20/3244; B01J20/3246; B01J20/3257; B01J20/3259; B01J20/3268; B01J20/3272; B01J20/328; B01J2220/00; B01J2220/50; B01J2220/54; B01J2220/56; B01J2220/58; Y; Y10; Y10T; Y10T428/00; Y10T428/29; Y10T428/2982; Y10T428/2991; Y10T428/2993; Y10T428/2996
Claims Analysis
Total Claims: 21
Claim 1
Independent Claim
97 words
A support for the size separation of cationic polymers which comprises a rigid, non-swellable controlled porosity support of the formula: ##STR5## wherein R 4 may be a hydrocarbon chain containing one to eight carbon units per quaternizable X group or a single aryl ring; R 8 , r 9 and R 10 each may be a hydrocarbon chain containing one to four carbon units per quaternized group or other hydrophilic group or a single aryl ring; Si 1 may be a silicon atom on the support surface or on an adjacent silane moiety; and, X is halogen.
Claim 2
Dependent Claim
97 words
A support for the size separation of cationic polymers which comprises a rigid, non-swellable controlled porosity support of the formula: ##STR5## wherein R 4 may be a hydrocarbon chain containing one to eight carbon units per quaternizable X group or a single aryl ring; R 8 , r 9 and R 10 each may be a hydrocarbon chain containing one to four carbon units per quaternized group or other hydrophilic group or a single aryl ring; Si 1 may be a silicon atom on the support surface or on an adjacent silane moiety; and, X is halogen.
Claim 3
Dependent Claim
27 words
A support as in claim 1 wherein R 4 is a hydrocarbon chain containing one to four carbon units per quaternizable X group and X is chloro.
Claim 4
Dependent Claim
71 words
A gel permeation chromatographic method for the separation of molecular weight fractions of a cationic polymer which comprises passing a solution of said polymer through a porous chromatography bed of a rigid, non-swellable, controlled porosity glass support having a porosity of from about 50 to about 25,000 Angstroms, said support having a quaternized siliceous surface which is prepared by treating the siliceous surface with a silane compound and a quaternizing agent.
Claim 5
Dependent Claim
71 words
A gel permeation chromatographic method for the separation of molecular weight fractions of a cationic polymer which comprises passing a solution of said polymer through a porous chromatography bed of a rigid, non-swellable, controlled porosity glass support having a porosity of from about 50 to about 25,000 Angstroms, said support having a quaternized siliceous surface which is prepared by treating the siliceous surface with a silane compound and a quaternizing agent.
Claim 6
Dependent Claim
31 words
A gel permeation chromatography method as in claim 3 wherein the cationic polymer is a homopolymer or a copolymer which contains at least about 1 weight percent of net cationic constituents.
Claim 7
Dependent Claim
24 words
A gel permeation chromatography method as in claim 3 wherein the molecular weight fractions are successively eluted from said gel chromatography bed and collected.
Claim 8
Dependent Claim
87 words
A gel permeation chromatography method as in claim 3 wherein the silane compound is a compound of the formula: ##STR6## wherein R 1 , R 2 and R 3 each may be halogen, hydroxy, alkoxy, aryloxy, or an alkyl or aryl ester; R 4 may be a hydrocarbon chain containing one to eight carbon units per quaternizable X group or a single aryl ring; R 5 and R 6 each may be hydrogen or a hydrocarbon chain containing one to four carbon units; and, X is halogen.
Claim 9
Dependent Claim
30 words
A gel permeation chromatography method as in claim 6 wherein R 4 is a hydrocarbon chain containing one to four carbon units per quaternizable X group and X is chloro.
Claim 10
Dependent Claim
15 words
A gel permeation chromatography method as in claim 6 wherein the silane compound is 3-aminopropyltriethoxysilane.
Claim 11
Dependent Claim
60 words
A gel permeation chromatography method as in claim 3 wherein the quaternizing agent is a compound of the formula: ##STR7## wherein R 7 , R 8 , R 9 and R 10 each may be a hydrocarbon chain containing one to four carbon units per quaternized group or other hydrophilic group or a single aryl ring; and, X is halogen.
Claim 12
Dependent Claim
16 words
A gel permeation chromatography method as in claim 9 wherein the quaternizing agent is 1-chloro-2-hydroxy-3-(trimethylammonium) chloride.
Claim 13
Dependent Claim
129 words
A gel permeation chromatographic method for the separation of molecular weight fractions of a cationic polymer which comprises passing a solution of said polymer through a porous chromatography bed of a rigid, non-swellable, controlled porosity glass support having a porosity of from about 50 to about25,000 Angstroms, said support having the formula: ##STR8## wherein R 4 may be a hydrocarbon chain containing one to eight carbon units per quaternizable X group or a single aryl ring; R 8 , r 9 and R 10 each may be a hydrocarbon chain containing one to four carbon units per quaternized group or other hydrophilic group or a single aryl ring; Si 1 may be a silicon atom on the support surface or on an adjacent silane moiety; and, X is halogen.
Claim 14
Dependent Claim
129 words
A gel permeation chromatographic method for the separation of molecular weight fractions of a cationic polymer which comprises passing a solution of said polymer through a porous chromatography bed of a rigid, non-swellable, controlled porosity glass support having a porosity of from about 50 to about25,000 Angstroms, said support having the formula: ##STR8## wherein R 4 may be a hydrocarbon chain containing one to eight carbon units per quaternizable X group or a single aryl ring; R 8 , r 9 and R 10 each may be a hydrocarbon chain containing one to four carbon units per quaternized group or other hydrophilic group or a single aryl ring; Si 1 may be a silicon atom on the support surface or on an adjacent silane moiety; and, X is halogen.
Claim 15
Dependent Claim
30 words
A gel permeation chromatographic method as in claim 11 wherein R 4 is a hydrocarbon chain containing one to four carbon units per quaternizable X group and X is chloro.
Claim 16
Dependent Claim
67 words
A quaternized controlled porosity glass support for the size separation of cationic polymers which comprises a rigid, non-swellable, controlled porosity glass support having a porosity of from about 50 to about 25,000 Angstroms, said support having a quaternized siliceous surface which is prepared by treating the siliceous surface with a silane compound and a quaternizing agent wherein the silane compound is a compound of the formula: ##STR9##
Claim 17
Dependent Claim
67 words
A quaternized controlled porosity glass support for the size separation of cationic polymers which comprises a rigid, non-swellable, controlled porosity glass support having a porosity of from about 50 to about 25,000 Angstroms, said support having a quaternized siliceous surface which is prepared by treating the siliceous surface with a silane compound and a quaternizing agent wherein the silane compound is a compound of the formula: ##STR9##
Claim 18
Dependent Claim
30 words
A quaternized porous glass support as in claim 13 wherein R 4 is a hydrocarbon chain containing one to four carbon units per quaternizable X group and X is chloro.
Claim 19
Dependent Claim
15 words
A quaternized porous glass support as in claim 13 wherein the silane compound is 3-aminopropyltriethoxysilane.
Claim 20
Dependent Claim
60 words
A quaternized porous glass support as in claim 13 wherein the quaternizing agent is a compound of the formula: ##STR10## wherein R 7 , R 8 , R 9 and R 10 each may be a hydrocarbon chain containing one to four carbon units per quaternized group or other hydrophilic group or a single aryl ring; and, X is halogen.
Claim 21
Dependent Claim
16 words
A quaternized porous glass support as in claim 16 wherein the quaternizing agent is 1-chloro-2-hydroxy-3-(trimethylammonium) chloride.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1981-10-02 | 1982-04-03 | 1982-10-03 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1985-10-02 | 1986-04-03 | 1986-10-03 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1989-10-02 | 1990-04-03 | 1990-10-03 | $7700.00 | Window Closed / Lapsed |