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US4116841A Expired / Lapsed US ⏱️ 0.0 years remaining

Semipermeable membrane mass transfer apparatus having collapsed membrane about support members

Assignee: Baxter International Inc
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Filing: 1977-03-21
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Granted: 1978-09-26
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Expires: 1997-03-21
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Abstract

Abstract A mass transfer apparatus is disclosed comprising a housing, preferably rectangular, a semipermeable membrane disposed within said housing, said membrane being folded to form a stack of accordion pleats over the whole internal surface of the bottom of said housing, one or more support members being disposed within every pleat on one side only of said membrane, all edges of said membrane being embedded in plastic embedding material within said housing so that the membrane thereby forms two fluid compartments with ports allowing the flow of a fluid in each compartment, the creases of said membrane pleats being collapsed upon said support members and, at their ends, being sharply folded upon themselves and deeply penetrating into the embedding material along a longitudinal side of the housing. The creases which sharply fold upon themselves have a bi-concave external shape. A method of manufacturing the apparatus is also disclosed, comprising the following steps: (a) Making up an assemblage comprising a semipermeable membrane folded in an accordion-like manner into a number of closely spaced pleats around support members inserted on one side of said membrane; (b) Sealing certain edges of the membrane along substantially their whole length to form a first fluid-tight compartment disposed on the same side of the membrane as the support members and provided with at least one port, the pleats formed around the support members being in communication with the outside through such port; (c) Connecting said first compartment to a vacuum source and drawing a vacuum in said first compartment to collapse the membrane pleats about the edges of the support members along one side of the accordion stack, after first treating such membrane pleats with a suitable softening agent to increase the pliability of the membrane, where such softening treatment is deemed necessary or desirable; and (d) Applying a solidifiable fluid plastic material over the longitudinal face of the stack, on the side where the membrane pleats are both open and without exposed support members, and solidifying said plastic material to embed the membrane pleats in such collapsed condition, thus forming a second compartment with at least one port and without bypass channels.

Inventors

  • 👤 Alexander S. Borsanyi

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-11-02 15:01
CPC Classifications
B; B01; B01D; B01D63/00; B01D63/14

Claims Analysis

Total Claims: 31
Claim 1
Independent Claim 197 words
A mass transfer apparatus comprising a housing formed at least in part of solidified plastic material, a semipermeable membrane disposed within said housing, said membrane being folded to form a stack of accordion pleats, support members being disposed within the pleats on one side of the membrane, the ends, top and bottom and the sides of the stack being sealed to the housing except at longitudinally spaced side regions defining inlet and outlet regions on both sides of the stack, whereby two fluid compartments divided by said membrane are formed in the stack with each fluid compartment having longitudinally spaced inlet and outlet regions, the housing being provided with longitudinally spaced inlet and outlet ports individually communicating with said inlet and outlet regions enabling a fluid to be passed through each fluid compartment, those pleats of said membrane which receive said support members extending about longitudinal edges of said support members to define longitudinal creases, said creases being collapsed upon themselves and upon said longitudinal edges of said support members and being embedded in such collapsed condition in said solidified plastic material of said housing, thereby eliminating bypass channels in the compartment devoid of said support members.
Claim 2
Dependent Claim 197 words
A mass transfer apparatus comprising a housing formed at least in part of solidified plastic material, a semipermeable membrane disposed within said housing, said membrane being folded to form a stack of accordion pleats, support members being disposed within the pleats on one side of the membrane, the ends, top and bottom and the sides of the stack being sealed to the housing except at longitudinally spaced side regions defining inlet and outlet regions on both sides of the stack, whereby two fluid compartments divided by said membrane are formed in the stack with each fluid compartment having longitudinally spaced inlet and outlet regions, the housing being provided with longitudinally spaced inlet and outlet ports individually communicating with said inlet and outlet regions enabling a fluid to be passed through each fluid compartment, those pleats of said membrane which receive said support members extending about longitudinal edges of said support members to define longitudinal creases, said creases being collapsed upon themselves and upon said longitudinal edges of said support members and being embedded in such collapsed condition in said solidified plastic material of said housing, thereby eliminating bypass channels in the compartment devoid of said support members.
Claim 3
Dependent Claim 42 words
A mass transfer apparatus according to claim 1, wherein said housing is formed in part of solidified plastic material and also includes an outer part which extends about said stack and about the solidified plastic material embedding the creases of the membrane.
Claim 4
Dependent Claim 21 words
A mass transfer apparatus according to claim 1, wherein said creases which sharply fold upon themselves have a bi-concave external shape.
Claim 5
Dependent Claim 19 words
A mass transfer apparatus according to claim 1, wherein said apparatus is adapted for use in hemodialysis and/or ultrafiltration.
Claim 6
Dependent Claim 166 words
A method of manufacturing the apparatus as defined in claim 1 comprising the following steps: (a) making an assembly by folding a semipermeable membrane into a number of closely spaced pleats around perforated support members on one side of said membrane; (b) making from the membrane a first fluid-tight compartment by providing a seal over all pleat folds on said one side of said membrane and the edges of the membrane, and providing said compartment with at least one port; (c) connecting said first compartment to a vacuum source and applying vacuum to said first compartment forming creases in those portions of the pleats folded about edges of said support members; and (d) applying a solidifiable fluid material over the said creases while said vacuum is applied, and solidifying said fluid material, thus forming a second compartment in which said creases are embedded, and also providing shape-sustaining support by the solidized fluid material for the creases, and providing said second compartment with at least one port.
Claim 7
Dependent Claim 22 words
A method according to claim 5, comprising treating at least a part of the membrane to soften the same before applying vacuum.
Claim 8
Dependent Claim 17 words
A method according to claim 6, in which said treating step comprises wetting the membrane with water.
Claim 9
Dependent Claim 21 words
A method according to claim 6, in which only the creases of the membrane pleats are softened in said treating step.
Claim 10
Dependent Claim 16 words
A method according to claim 7, in which vacuum is maintained until the membrane is dried.
Claim 11
Dependent Claim 18 words
A method according to claim 5, in which said vacuum is maintained until said plastic material has solidified.
Claim 12
Dependent Claim 11 words
A method according to claim 5, wherein the membrane is Cuprophan.
Claim 13
Dependent Claim 11 words
A method according to claim 5, wherein the membrane is polyacrylonitrile.
Claim 14
Dependent Claim 11 words
A method according to claim 5, wherein the member polyolefin. polycarbonate.
Claim 15
Dependent Claim 96 words
A mass transfer apparatus comprising a semipermeable membrane folded to form a stack of accordion pleats, support members disposed within the pleats of said folded membrane, and means embedding the edges of said pleats, wherein the improvement comprises: at least some of the pleats of said membrane having folded edge portions which project beyond the side edges of the support members received therein; each said projecting folded edge portion of said membrane collapsed upon itself and against the edge of the support member received therein and being embedded in said collapsed condition by said embedding means.
Claim 16
Dependent Claim 96 words
A mass transfer apparatus comprising a semipermeable membrane folded to form a stack of accordion pleats, support members disposed within the pleats of said folded membrane, and means embedding the edges of said pleats, wherein the improvement comprises: at least some of the pleats of said membrane having folded edge portions which project beyond the side edges of the support members received therein; each said projecting folded edge portion of said membrane collapsed upon itself and against the edge of the support member received therein and being embedded in said collapsed condition by said embedding means.
Claim 17
Dependent Claim 16 words
The apparatus of claim 14, wherein the projecting folded edge portions have a bi-concave external shape.
Claim 18
Dependent Claim 18 words
A mass transfer apparatus according to claim 14, wherein said support members are of non-woven plastic mesh construction.
Claim 19
Dependent Claim 17 words
A mass transfer apparatus according to claim 14, wherein the membrane is adapted for hemodialysis and/or ultrafiltration.
Claim 20
Independent Claim 117 words
A method of manufacturing a mass transfer apparatus comprising the following steps: (a) making an assembly by folding a semipermeable membrane into a number of closely spaced accordion pleats around support members disposed adjacent one side of said membrane, at least some of the pleats having folded edge portions projecting beyond the edges of said support members received therein; (b) drawing a vacuum within the folds of said pleats which open to said one side of said membrane to collapse said projecting folded edge portions; (c) embedding said projecting folded edge portions while they are so collapsed in a solidifiable fluid material; and (d) allowing said material to solidify while said folded edge portions are so collapsed.
Claim 21
Independent Claim 117 words
A method of manufacturing a mass transfer apparatus comprising the following steps: (a) making an assembly by folding a semipermeable membrane into a number of closely spaced accordion pleats around support members disposed adjacent one side of said membrane, at least some of the pleats having folded edge portions projecting beyond the edges of said support members received therein; (b) drawing a vacuum within the folds of said pleats which open to said one side of said membrane to collapse said projecting folded edge portions; (c) embedding said projecting folded edge portions while they are so collapsed in a solidifiable fluid material; and (d) allowing said material to solidify while said folded edge portions are so collapsed.
Claim 22
Dependent Claim 25 words
The method of claim 18, wherein the extent of said vacuum is substantially the same as the negative pressure of the apparatus in operating condition.
Claim 23
Dependent Claim 24 words
A method according to claim 18, comprising treating at least said folded edge portions of the membrane to soften the same before applying vacuum.
Claim 24
Dependent Claim 24 words
A method according to claim 20, in which said treating step comprises wetting at least said folded edge portions of the membrane with water.
Claim 25
Dependent Claim 18 words
A method according to claim 20, in which said vacuum is maintained until said plastic material has solidified.
Claim 26
Dependent Claim 177 words
A method of manufacturing the apparatus as defined in claim 1 comprising the following steps: (a) making up an assemblage comprising a semipermeable membrane folded in an accordion-like manner into a number of closely spaced pleats around support members inserted on one side only of said membrane; (b) enclosing said assemblage and sealing edges of the membrane along their whole length to define a first fluid-tight compartment disposed on the same side as the support members with respect to the membrane and provided with at least one port, the pleats formed around the support members in said first compartment communicating through said port with the outside; (c) connecting said first compartment to a vacuum source and applying the vacuum to said first compartment; and (d) applying a solidifiable fluid plastic material to said assemblage on the side thereof where the membrane pleats are both open and devoid of support members while said vacuum is so applied, and solidifying said plastic material, thus forming a second compartment free of bypass channels between said solidified plastic and said membrane.
Claim 27
Dependent Claim 26 words
A method according to claim 23, comprising the additional step of treating at least a part of the membrane to soften the same before applying vacuum.
Claim 28
Dependent Claim 17 words
A method according to claim 24, in which said treating step comprises wetting the membrane with water.
Claim 29
Dependent Claim 21 words
A method according to claim 24, in which only the creases of the membrane pleats are softened in said treating step.
Claim 30
Dependent Claim 16 words
A method according to claim 25, in which vacuum is maintained until the membrane is dried.
Claim 31
Dependent Claim 17 words
A method according to claim 24, in which vacuum is maintained until said plastic material has solidified.

References Cited (Backward Citations)

US3827565A Cited
US3788482A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1981-09-25 1982-03-27 1982-09-26 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1985-09-25 1986-03-27 1986-09-26 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1989-09-25 1990-03-27 1990-09-26 $7700.00 Window Closed / Lapsed

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