US4111944A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Anti-hyperuricemia composition
Assignee: Merck and Co Inc
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Filing: 1977-06-21
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Granted: 1978-09-05
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Expires: 1997-06-21
Abstract
Abstract Compositions useful in the treatment of gout and hyperuricemia and containing a substituted 1,2,4-triazole as the active ingredient are provided, the triazoles being substituted at the 5 position with a pyridyl radical and at the 3 position with a phenyl or a pyridyl radical. Methods of preparing these substituted triazoles are described. Certain of the compounds are novel.
Inventors
- 👤 Frederick C. Novello
- 👤 John J. Baldwin
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-09 04:26
CPC Classifications
C; C07; C07D; C07D401/00; C07D401/02; C07D401/12; C07D401/14; C07D401/04
Claims Analysis
Total Claims: 5
Claim 1
Independent Claim
52 words
A compound of the formula: ##STR3## wherein R 1 is lower alkyl; R 3 is phenyl, lower alkylphenyl, tri-lower alkylphenyl, 4-pyridyl, mono-lower alkyl-4-pyridyl or di-lower alkyl-4-pyridyl; and R 5 is 4-pyridyl, mono-lower alkyl-4-pyridyl or di-lower alkyl-4-pyridyl, including the mono-N-oxides of those products wherein R 3 and R 5 are both a pyridyl.
Claim 2
Dependent Claim
52 words
A compound of the formula: ##STR3## wherein R 1 is lower alkyl; R 3 is phenyl, lower alkylphenyl, tri-lower alkylphenyl, 4-pyridyl, mono-lower alkyl-4-pyridyl or di-lower alkyl-4-pyridyl; and R 5 is 4-pyridyl, mono-lower alkyl-4-pyridyl or di-lower alkyl-4-pyridyl, including the mono-N-oxides of those products wherein R 3 and R 5 are both a pyridyl.
Claim 3
Dependent Claim
32 words
An N-oxide of a compound having the formula: ##STR4## wherein R 1 is lower alkyl; R 3 is 4-pyridyl, mono-lower alkyl-4-pyridyl or di-lower alkyl-4-pyridyl; and R 5 is 4-pyridyl or lower alkyl-4-pyridyl.
Claim 4
Dependent Claim
32 words
An N-oxide of a compound having the formula: ##STR4## wherein R 1 is lower alkyl; R 3 is 4-pyridyl, mono-lower alkyl-4-pyridyl or di-lower alkyl-4-pyridyl; and R 5 is 4-pyridyl or lower alkyl-4-pyridyl.
Claim 5
Dependent Claim
16 words
A compound as claimed in claim 1 wherein R 3 and R 5 each represent 4-pyridyl.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1981-09-04 | 1982-03-06 | 1982-09-05 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1985-09-04 | 1986-03-06 | 1986-09-05 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1989-09-04 | 1990-03-06 | 1990-09-05 | $7700.00 | Window Closed / Lapsed |